C
Cestmir Cejka
Researcher at Academy of Sciences of the Czech Republic
Publications - 36
Citations - 1078
Cestmir Cejka is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Cornea & Corneal epithelium. The author has an hindex of 17, co-authored 36 publications receiving 923 citations. Previous affiliations of Cestmir Cejka include Charles University in Prague & Czech Technical University in Prague.
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Journal Article
UV Rays, the prooxidant/antioxidant imbalance in the cornea and oxidative eye damage.
TL;DR: The decrease of corneal antioxidant protective mechanisms results in oxidative injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive oxygen species generated by them.
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A Comparative Study of the Therapeutic Potential of Mesenchymal Stem Cells and Limbal Epithelial Stem Cells for Ocular Surface Reconstruction
Vladimir Holan,Vladimir Holan,Peter Trosan,Peter Trosan,Cestmir Cejka,Cestmir Cejka,Eliska Javorkova,Eliska Javorkova,Alena Zajicova,Barbora Hermankova,Barbora Hermankova,Milada Chudíčková,Milada Chudíčková,Jitka Cejkova +13 more
TL;DR: Results show that BM‐MSCs' therapeutic effect on healing of injured corneal surface is comparable to that of tissue‐specific LSCs, and suggest that BM-MSCs can be used for ocular surface regeneration in cases when autologous L SCs are absent or difficult to obtain.
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Oxidative stress to the cornea, changes in corneal optical properties, and advances in treatment of corneal oxidative injuries.
Cestmir Cejka,Jitka Cejkova +1 more
TL;DR: The role of oxidativestress in the pathogenesis of ocular diseases with particular attention to oxidative stress in the cornea and changes in corneal optical properties are discussed and advances in the treatment of corneAL oxidative injuries or diseases are shown.
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Suppression of alkali-induced oxidative injury in the cornea by mesenchymal stem cells growing on nanofiber scaffolds and transferred onto the damaged corneal surface.
Jitka Cejkova,Peter Trosan,Peter Trosan,Cestmir Cejka,Cestmir Cejka,A Lencova,Alena Zajicova,Eliska Javorkova,Eliska Javorkova,Šárka Kubinová,Eva Syková,Vladimir Holan,Vladimir Holan +12 more
TL;DR: MSCs on nanofiber scaffolds protected the formation of toxic peroxynitrite, lowered apoptotic cell death and decreased matrix metalloproteinase and pro-inflammatory cytokine production and significantly accelerated corneal healing.
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Decreased expression of antioxidant enzymes in the conjunctival epithelium of dry eye (Sjögren's syndrome) and its possible contribution to the development of ocular surface oxidative injuries.
TL;DR: It is suggested that the decreased expression of antioxidant enzymes in dry eye disease (SS) contributes to the development of anterior eye surface oxidative injuries.