Jo Varley-Campbell

TL;DR: If a shared model of the literature searching process can be detected across systematic review guidance documents and, if so, how this process is reported in the guidance and supported by published studies is determined.

TL;DR: LDCT screening may be clinically effective in reducing lung cancer mortality, but there is considerable uncertainty about the effect on costs and the magnitude of benefits, and screening programmes are predicted to be more effective than no screening, reduce lungcancer mortality and result in more lung cancer diagnoses.

TL;DR: A new discrete time-state transition economic model (semi-Markov) was developed, with acute rejection, graft function (GRF) and new-onset diabetes mellitus used to extrapolate graft survival.

TL;DR: Although cetuximab and panitumumab in combination with chemotherapy appear to be clinically beneficial for RAS WT patients compared with chemotherapy alone, they are likely to represent poor value when judged by cost-effectiveness criteria currently used in the UK.

TL;DR: Limb immobilisation results in non-uniform loss of isometric muscle strength, size and NMF over time, and different outcomes between upper and lower limbs could be attributed to higher degrees of central neural control of upper limb musculature.