Joana S Cruz-Pereira

TL;DR: Future studies will focus on understanding the mechanisms underlying the microbiota-gut-brain axis and attempt to elucidate microbial-based intervention and therapeutic strategies for neuropsychiatric disorders.

TL;DR: This review integrates the available data from animal and human studies on these three factors in the etiology and progression of depression and focuses on the processes by which this microbiota-immune-stress matrix may influence centrally mediated events and on possible therapeutic interventions to correct imbalances in this triune.

TL;DR: In this article , a prebiotic dietary intervention was shown to improve the behavioral response to stress in aged mice, not through amelioration of the inflammatory response, but by restoring the levels of key metabolites in prefrontal cortex of aged animals.

TL;DR: In this article , the authors assessed the impact of gut microbiota depletion, using an antibiotic cocktail, on aging and its impact on social behavior and the immune system and concluded that the aged gut microbiota can be specifically targeted to affect social deficits.