Joshua M. Lyte

TL;DR: Future studies will focus on understanding the mechanisms underlying the microbiota-gut-brain axis and attempt to elucidate microbial-based intervention and therapeutic strategies for neuropsychiatric disorders.

TL;DR: Administration of SCFAs to mice undergoing psychosocial stress alleviates enduring alterations in anhedonia and heightened stress‐responsiveness, as well as stress‐induced increases in intestinal permeability, informing the development of microbiota‐targeted therapies for stress‐related disorders.

TL;DR: Kfir can signal through the microbiota-gut-immune-brain axis and modulate host behaviour and support the broadening of the definition of psychobiotic to include kefir fermented foods.

TL;DR: The volatility of the microbiome is significantly correlated with several readouts of the stress response, including behaviour and corticosterone response, and inter-species similarities in the microbiome stress response on a functional level are found.

TL;DR: It was shown that mice behaviourally susceptible to stress (indexed by a reduction in social interaction behaviour) had higher plasma corticosterone levels and adrenal hypertrophy, and prefrontal cortex mRNA expression of corticotrophin-releasing factor was increased in susceptible mice relative to resilient mice.