J
Jodi Layton
Researcher at Johns Hopkins University
Publications - 4
Citations - 202
Jodi Layton is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Proinflammatory cytokine & Transplantation. The author has an hindex of 3, co-authored 4 publications receiving 199 citations.
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Passive transfer of alloantibodies restores acute cardiac rejection in IgKO mice.
Barbara A. Wasowska,Zhiping Qian,D. Cangello,E Behrens,Khanh Van Tran,Jodi Layton,Fred Sanfilippo,William M. Baldwin +7 more
TL;DR: A model of alloantibody-mediated graft injury is established using B10.A hearts transplanted to wild type or immunoglobulin knock out (IgKO) mice, indicating that macrophage- and T-cell-dependent immune responses were intact in IgKO recipients.
Journal ArticleDOI
Non-complement- and complement-activating antibodies synergize to cause rejection of cardiac allografts.
Salma Rahimi,Zhiping Qian,Jodi Layton,Karen Fox-Talbot,William M. Baldwin,Barbara A. Wasowska +5 more
TL;DR: Non‐complement‐activating AlloAbs stimulate endothelial cells to produce chemokines and this effect is augmented in the milieu of proinflammatory cytokines, indicating that non-complement •activating •AlloAbs can augment injury to allografts by complement‐activated Allo Abs.