J
Jodi Murakami
Researcher at City of Hope National Medical Center
Publications - 7
Citations - 477
Jodi Murakami is an academic researcher from City of Hope National Medical Center. The author has contributed to research in topics: Haematopoiesis & Stromal cell. The author has an hindex of 5, co-authored 7 publications receiving 343 citations. Previous affiliations of Jodi Murakami include Beckman Research Institute & University of Hawaii.
Papers
More filters
Journal ArticleDOI
Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion
Bijender Kumar,Mayra Garcia,Lihong Weng,Xiaoman Jung,Jodi Murakami,Xingbin Hu,Xingbin Hu,Tinisha McDonald,Allen Lin,A. R. Kumar,D. L. Digiusto,Anthony S. Stein,Vinod Pullarkat,S.K. Hui,Nadia Carlesso,Ya-Huei Kuo,Ravi Bhatia,Guido Marcucci,Ching-Cheng Chen +18 more
TL;DR: Evidence is provided that acute myeloid leukemia (AML) blasts remodel the BM niche into a leukemia growth-permissive and normal hematopoiesis-suppressive microenvironment through exosome secretion, and novel features of AML pathogenesis are uncovered.
Journal ArticleDOI
Exosome-mediated microenvironment dysregulation in leukemia.
TL;DR: Recent works that decipher the normal hematopoietic niche cellular components are summarized and how the leukemia-transformed niche contributes to hematological malignances is described.
Journal ArticleDOI
Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche.
Xingbin Hu,Mayra Garcia,Lihong Weng,Xiaoman Jung,Jodi Murakami,Jodi Murakami,Bijender Kumar,Charles Warden,Ivan Todorov,Ching-Cheng Chen,Ching-Cheng Chen +10 more
TL;DR: The results indicate that Sca1+ progenitors, through the generation of both osteogenic and stromal cells, provide a supportive environment for hematopoiesis.
Journal ArticleDOI
Evidence for direct binding between HetR from Anabaena sp. PCC 7120 and PatS-5.
Erik A. Feldmann,Shuisong Ni,Indra D. Sahu,Clay H. J. Mishler,Douglas D. Risser,Jodi Murakami,Sasa K. Tom,Robert M. McCarrick,Gary A. Lorigan,Blanton S. Tolbert,Sean M. Callahan,Michael A. Kennedy +11 more
TL;DR: Experimental evidence for direct binding between HetR and the C-terminal RGSGR pentapeptide, PatS-5 is reported and it is indicated that Pats-5 disrupted Hetr binding to DNA through a direct Het R/PatS interaction.
Journal ArticleDOI
Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1.
Jodi Murakami,Jodi Murakami,Baohui Xu,Christopher B. Franco,Xingbin Hu,Xingbin Hu,Stephen J. Galli,Irving L. Weissman,Ching-Cheng Chen,Ching-Cheng Chen +9 more
TL;DR: A subset of hematopoietic stem cells (HSCs) in the bone marrow (BM) that expressed β7 integrin were capable of multilineage, long-term reconstitution and had an inherent competitive advantage over β7− HSCs.