J
Joel M. Dulhunty
Researcher at University of Queensland
Publications - 74
Citations - 2597
Joel M. Dulhunty is an academic researcher from University of Queensland. The author has contributed to research in topics: Intensive care & Intensive care unit. The author has an hindex of 24, co-authored 70 publications receiving 2140 citations. Previous affiliations of Joel M. Dulhunty include Queensland University of Technology & Royal Brisbane and Women's Hospital.
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Journal ArticleDOI
Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicenter double-blind, randomized controlled trial
Joel M. Dulhunty,Jason A. Roberts,Joshua S. Davis,Steven A R Webb,Rinaldo Bellomo,Charles D. Gomersall,Charudatt Shirwadkar,Glenn M Eastwood,John Myburgh,David L. Paterson,Jeffrey Lipman +10 more
TL;DR: Continuous administration of beta-lactam antibiotics achieved higher plasma antibiotic concentrations than intermittent administration with improvement in clinical cure, providing a strong rationale for further multicenter trials with sufficient power to identify differences in patient-centered endpoints.
Journal ArticleDOI
Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials
Jason A. Roberts,Mohd H. Abdul-Aziz,Joshua S. Davis,Joel M. Dulhunty,Menino O. Cotta,John Myburgh,Rinaldo Bellomo,Jeffrey Lipman +7 more
TL;DR: Compared with intermittent dosing, administration of β-lactam antibiotics by continuous infusion in critically ill patients with severe sepsis is associated with decreased hospital mortality and factors associated with hospital mortality in multivariable analysis.
Journal ArticleDOI
A Multicenter Randomized Trial of Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis.
Joel M. Dulhunty,Jason A. Roberts,Joshua S. Davis,Steven A R Webb,Rinaldo Bellomo,Charles D. Gomersall,Charudatt Shirwadkar,Glenn M Eastwood,John Myburgh,David L. Paterson,Therese Starr,Sanjoy K. Paul,Jeffrey Lipman +12 more
TL;DR: In critically ill patients with severe sepsis, there was no difference in outcomes between β-lactam antibiotic administration by continuous and intermittent infusion.
Journal ArticleDOI
Impact of blood product transfusion on short and long-term survival after cardiac surgery: more evidence.
TL;DR: It is suggested that blood or blood product transfusion during or after cardiac surgery is associated with increased short-term and long-term mortality, and reinforces the need for prospective randomized controlled studies for evaluation of restrictive transfusion triggers and objective clinical indicators for transfusion in the cardiac surgical patient population.
Journal ArticleDOI
Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort
Mohd H. Abdul-Aziz,Jeffrey Lipman,Murat Akova,Matteo Bassetti,Jan J. De Waele,George Dimopoulos,Joel M. Dulhunty,Kirsi-Maija Kaukonen,Despoina Koulenti,Claude Martin,Philippe Montravers,Jordi Rello,Andrew Rhodes,Therese Starr,Steven C. Wallis,Jason A. Roberts +15 more
TL;DR: Analysis of this large dataset has provided additional data on the niche benefits of administration of piperacillin/tazobactam and meropenem by prolonged infusion in critically ill patients, particularly for patients with respiratory infections.