J
Joeri Bordes
Researcher at Max Planck Society
Publications - 11
Citations - 46
Joeri Bordes is an academic researcher from Max Planck Society. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications receiving 6 citations.
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Journal ArticleDOI
Chronic social defeat stress in female mice leads to sex-specific behavioral and neuroendocrine effects
Lotte van Doeselaar,Huanqing Yang,Joeri Bordes,L. Brix,Clara Engelhardt,Fiona Tang,Mathias V. Schmidt +6 more
TL;DR: There are differences in the way that female and male mice respond towards chronic social stress conditions when it comes to behavior and hormonal changes, which are partially dependent on estrous cycle stage.
Journal ArticleDOI
The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells
L. Brix,Alexander S. Häusl,Irmak Toksöz,Joeri Bordes,Lotte van Doeselaar,Clara Engelhardt,Sowmya V. Narayan,Margherita Springer,V. Sterlemann,Jan M. Deussing,Alon Chen,Mathias V. Schmidt +11 more
TL;DR: In this article , a combination of endogenous knockout and viral rescue was used to show that male mice lacking FKBP51 in Pomc-expressing cells exhibit enhanced glucocorticoid (GC)-mediated negative feedback and are protected from age-related disruption of their diurnal corticosterone (CORT) rhythm.
Journal ArticleDOI
Introducing a depression-like syndrome for translational neuropsychiatry: a plea for taxonomical validity and improved comparability between humans and mice
Iven von Mücke-Heim,Lidia Urbina-Treviño,Joeri Bordes,Clemens Ries,Mathias V. Schmidt,Jan M. Deussing +5 more
TL;DR: In this paper , a taxonomical concept for modelling depression in laboratory mice, which is called depression-like syndrome (DLS), was introduced, based on growing evidence suggesting that mice possess advanced socioemotional abilities and can display non-random symptom patterns indicative of an evolutionary conserved disorder-like phenotype.
Posted ContentDOI
Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress
Joeri Bordes,Lucas Bernardes Miranda,Maya Reinhardt,L. Brix,Lotte van Doeselaar,Clara Engelhardt,Benno Pütz,Felix Agakov,Bertram Müller-Myhsok,Mathias V. Schmidt +9 more
TL;DR: Evidence is provided that the DeepOF supervised and unsupervised pipelines detect a distinct stress-induced social behavioral pattern, which was particularly observed at the beginning of a novel social encounter.
Journal ArticleDOI
Contribution of the co-chaperone FKBP51 in the ventromedial hypothalamus to metabolic homeostasis in male and female mice
L. Brix,Irmak Toksöz,London K Aman,Veronika Kovarova,Margherita Springer,Joeri Bordes,Lotte van Doeselaar,Clara Engelhardt,Alexander S. Häusl,Sowmya V. Narayan,V. Sterlemann,Huanqing Yang,Jan M. Deussing,Mathias V. Schmidt +13 more
TL;DR: In this paper , the role of FKBP51 in the ventromedial hypothalamus (VMH) was investigated by conditional deletion and virus-mediated overexpression of SF1-positive neurons.