J
Johan Baner
Researcher at Natera
Publications - 32
Citations - 3399
Johan Baner is an academic researcher from Natera. The author has contributed to research in topics: Biological Father & Trisomy. The author has an hindex of 22, co-authored 32 publications receiving 3259 citations. Previous affiliations of Johan Baner include Uppsala University & Stanford University.
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Journal ArticleDOI
Multiplexed genotyping with sequence-tagged molecular inversion probes
Paul Hardenbol,Johan Baner,Maneesh Jain,Mats Nilsson,Eugeni Namsaraev,George Karlin-Neumann,Hossein Fakhrai-Rad,Mostafa Ronaghi,Thomas D. Willis,Ulf Landegren,Ronald W. Davis +10 more
TL;DR: The development of molecular inversion probe (MIP) genotyping is reported on, an efficient technology for large-scale single nucleotide polymorphism (SNP) analysis and multiplex analysis of more than 1,000 probes in a single tube can be done using standard laboratory equipment.
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Signal amplification of padlock probes by rolling circle replication
TL;DR: This work found the Phi29 DNA polymerase to be superior to the Klenow fragment in displacing the target DNA strand, and it maintained the polymerization reaction for at least 12 h, yielding an extension product that represents several thousand-fold the length of the padlock probe.
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Noninvasive prenatal aneuploidy testing of chromosomes 13, 18, 21, X, and Y, using targeted sequencing of polymorphic loci.
Bernhard Zimmermann,Matthew Hill,George Gemelos,Zachary Demko,Milena Banjevic,Johan Baner,Allison M. Ryan,Styrmir Sigurjonsson,Nikhil Chopra,Michael Dodd,Brynn Levy,Matthew Rabinowitz +11 more
TL;DR: This study aims to develop a noninvasive prenatal test on the basis of the analysis of cell‐free DNA in maternal blood to detect fetal aneuploidy at chromosomes 13, 18, 21, X, and Y.
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Circle-to-circle amplification for precise and sensitive DNA analysis
TL;DR: A tightly controlled process for strand-specific amplification of circularized DNA molecules that is suitable for parallel amplification of large numbers of DNA circles, because the few cycles and the robust reaction mechanism preserves the proportion of amplified molecules.
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Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol
David S. Johnson,G. Gemelos,Johan Baner,Allison M. Ryan,Cengiz Cinnioglu,Milena Banjevic,R. Ross,M. Alper,B. Barrett,J. Frederick,D. Potter,Barry Behr,M. Rabinowitz +12 more
TL;DR: A major preclinical validation of a new method for PGS, termed ‘parental support’, is performed and it is found that the technology performs approximately as well as a metaphase karyotype.