Johan Garssen

TL;DR: Findings show that autism-like behaviour and its intestinal phenotype is associated with altered microbial colonization and activity in a murine model for ASD, with preponderance in male offspring, which open new avenues in the scientific trajectory of managing neurodevelopmental disorders by gut microbiome modulation.

TL;DR: An overview is presented on the underlying mechanisms of the effects of SCFAs on both immune and endothelial cells, including HDACs, FFA2 and FFA3 receptors and GPR109A regulation of nuclear factor‐kappa B activation and mitogen‐activated protein kinase (MAPK) signaling pathways.

TL;DR: A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and lactation.

TL;DR: It was determined that storing unprocessed breast milk at −80°C or 4°C caused death of cells present in breast milk, leading to contamination of the breast milk EV population with storage-induced EV, and an alternative method is proposed to store breast milk samples for EV analysis at later time points.

TL;DR: The use of pre-, pro- and synbiotics may result in a beneficial microbiota composition that might have a pivotal role on the prevention of several important diseases that develop in early life such as necrotizing enterocolitis and atopic eczema.