J
Johji Kato
Researcher at University of Miyazaki
Publications - 158
Citations - 5027
Johji Kato is an academic researcher from University of Miyazaki. The author has contributed to research in topics: Adrenomedullin & Blood pressure. The author has an hindex of 40, co-authored 154 publications receiving 4777 citations. Previous affiliations of Johji Kato include Matsumoto Dental University.
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Journal ArticleDOI
Adrenomedullin: A Possible Autocrine or Paracrine Inhibitor of Hypertrophy of Cardiomyocytes
Toshihiro Tsuruda,Johji Kato,Kazuo Kitamura,Kenji Kuwasako,Takuroh Imamura,Yasushi Koiwaya,Tetsuo Tsuji,Kenji Kangawa,Tanenao Eto +8 more
TL;DR: C cultured neonatal rat cardiomyocytes produce and secrete AM, and the secreted AM inhibits the protein synthesis of these cells, suggesting that AM may act on carduomyocytes as an autocrine or a paracrine factor modulating the cardiac growth.
Journal ArticleDOI
Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system
TL;DR: The identification of proangiotensin-12 suggests a processing cascade of the RA system, different from the cleavage of angiotens inogen to Ang I by renin.
Journal ArticleDOI
The intermediate form of glycine-extended adrenomedullin is the major circulating molecular form in human plasma.
Kazuo Kitamura,Johji Kato,Mari Kawamoto,Miho Tanaka,Naoyoshi Chino,Kenji Kangawa,Tanenao Eto +6 more
TL;DR: The present data indicate that most of circulating plasma AM immunoreactivity is occupied by AM-gly, an intermediate form of AM, which may reflect the process of production of AM in tissues.
Journal ArticleDOI
Plasma adrenomedullin concentration in patients with heart failure.
Johji Kato,Kunihisa Kobayashi,Takuma Etoh,Masashi Tanaka,Kazuo Kitamura,Takuroh Imamura,Yasushi Koiwaya,Kenji Kangawa,Tanenao Eto +8 more
TL;DR: A possible role for AM as a circulating hormone participating in the defense mechanism against further deterioration of congestive heart failure in patients with heart disease is suggested.
Journal ArticleDOI
Adrenomedullin: a protective factor for blood vessels.
TL;DR: A body of evidence suggests that AM participates in the mechanism against progression of vascular damage and remodeling, thereby alleviating the ischemia of tissues and organs.