J
Johji Miwa
Researcher at NEC
Publications - 12
Citations - 950
Johji Miwa is an academic researcher from NEC. The author has contributed to research in topics: Caenorhabditis elegans & Gene. The author has an hindex of 9, co-authored 12 publications receiving 915 citations. Previous affiliations of Johji Miwa include Chubu University.
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Journal ArticleDOI
Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans
TL;DR: It is reported that an atypical protein kinase C (PKC-3) is essential for proper asymmetric cell divisions and co-localizes with PAR-3 and concludes that PKC-3 plays an indispensable role in establishing embryonic polarity through interaction withPAR-3.
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The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans.
Ryuji Hosono,S. Hekimi,Yasuko Kamiya,T. Sassa,T. Sassa,S. Murakami,Kiyoji Nishiwaki,Johji Miwa,A. Taketo,K.-I. Kodaira +9 more
TL;DR: Results show that the unc‐18 gene plays a role in development as well as in the kinetics of ACh metabolism, and appears to be stage specific.
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The C. elegans unc-18 gene encodes a protein expressed in motor neurons.
Keiko Gengyo-Ando,Yasuko Kamiya,Ayanori Yamakawa,Ken-Ichi Kodaira,Kiyoji Nishiwaki,Johji Miwa,Isao Hori,Ryuji Hosono +7 more
TL;DR: Findings suggest that UNC-18 participates in the axonal transport system and influences the acetylcholine flow in motor neurons.
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Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance.
TL;DR: In Caenorhabditis elegans, prolonged nicotine treatment results in a long-lasting decrease in the abundance of nicotinic receptors that control egg-laying, which suggests that PKC-dependent signaling pathways may promote nicotine adaptation via regulation of Nicotinic receptor synthesis or degradation.
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Mutations in a protein kinase C homolog confer phorbol ester resistance on Caenorhabditis elegans
TL;DR: The predicted amino acid sequence revealed that the predicted tpa-1 protein sequence is highly similar to protein kinase C molecules from various animals, including man.