John Dixon

TL;DR: These updated guidelines reflect recent additions to the evidence base and include Examples of expanded topics in this update include: the roles of sleeve gastrectomy, bariatric surgery in patients with type‐2 diabetes,bariatric surgery for patients with mild obesity, copper deficiency, informed consent, and behavioral issues.

TL;DR: People randomized to surgical therapy were more likely to achieve remission of type 2 diabetes through greater weight loss, and these results need to be confirmed in a larger, more diverse population and have long-term efficacy assessed.

TL;DR: Moderate alcohol consumption seems to reduce the risk of NAFLD in the severely obese, possibly by reducing insulin resistance and systemic hypertension, features of the metabolic syndrome.

TL;DR: GPR54 is defined as a major control point in the reproductive axis and kisspeptin is suggested to be a neurohormonal effector, demonstrating that a key action ofkisspeptin on the hypothalamo-pituitary-gonadal axis occurs directly at the level of GnRH release.

TL;DR: In conclusion, weight loss after surgery provides major improvement or resolution of obesity and metabolic syndrome‐associated abnormal liver histological features in severely obese subjects.