J
John F. Bechberger
Researcher at University of British Columbia
Publications - 65
Citations - 3965
John F. Bechberger is an academic researcher from University of British Columbia. The author has contributed to research in topics: Gap junction & Connexin. The author has an hindex of 36, co-authored 65 publications receiving 3729 citations. Previous affiliations of John F. Bechberger include Stony Brook University & Southern Research Institute.
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Journal Article
A pre-loading method of evaluating gap junctional communication by fluorescent dye transfer.
TL;DR: Potent and reversible inhibitors of GJC can be used in this system to evaluate dye transfer within a given period of time.
Journal ArticleDOI
Evidence that disruption of connexon particle arrangements in gap junction plaques is associated with inhibition of gap junctional communication by a glycyrrhetinic acid derivative.
Gary S. Goldberg,Alonso P. Moreno,John F. Bechberger,Stephen S. Hearn,Richard R. Shivers,Daniel J. MacPhee,Yu Chun Zhang,Christian C. Naus +7 more
TL;DR: Evidence is presented that while exposure to glycyrrhetinic acid derivatives may not affect protein synthesis or location, it does seem to alter connexon particle packing in gap junction plaques.
Journal ArticleDOI
Tumor-Suppressive Effects of Pannexin 1 in C6 Glioma Cells
Charles P. Lai,John F. Bechberger,Roger J. Thompson,Brian A. MacVicar,Roberto Bruzzone,Christian C. Naus +5 more
TL;DR: It is shown that stable expression of Panx1 in C6 cells significantly reduced cell proliferation in monolayers, cell motility, anchorage-independent growth, and in vivo tumor growth in athymic nude mice.
Journal ArticleDOI
CCN3 (NOV) Interacts with Connexin43 in C6 Glioma Cells POSSIBLE MECHANISM OF CONNEXIN-MEDIATED GROWTH SUPPRESSION
TL;DR: Evidence is reported for an interaction of CCN3 with the C terminus of Cx43, which could play an important role in mediating growth control induced by specific gap junction proteins.
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Connexin43 null mutation increases infarct size after stroke
TL;DR: It is suggested that augmentation of GJIC in astrocytes may contribute to neuroprotection after ischemic injury.