Showing papers by "John G. Vandenbergh published in 2006"
TL;DR: The results indicate that non-reproductive, sexually dimorphic behavior is sensitive to endocrine disruption and suggest that both humans and wildlife are being exposed to levels of these endocrine disrupting compounds that are sufficient to disrupt the development of the nervous system and that may have permanent consequences on sexuallyDimorphic behaviors.
174 citations
TL;DR: TP-induced changes in neonatal AGD and infant areola number were reliable indicators of permanently altered adult phenotype in female Rats, and females in the two high-dose groups displayed increased incidences of external genital malformations and the presence of prostatic tissue, not normally found in female rats.
137 citations
TL;DR: It is demonstrated that exposure to EDCs during pre- and neonatal development can alter female adult neural phenotype and behavior related to monogamous behavior traits.
34 citations
01 Jan 2006
TL;DR: The role of pheromones in mammalian reproduction was discussed in this article, where it was shown that the onset of puberty can be accelerated or inhibited by priming pheroms, and once adulthood is reached, pheromes can influence the characteristics of the female ovarian cycle and induce a gonadotropin surge in the male.
Abstract: This chapter discusses the role of pheromones in mammalian reproduction. In several species, the onset of puberty can be accelerated or inhibited by priming pheromones, and once adulthood is reached, pheromones can influence the characteristics of the female's ovarian cycle and induce a gonadotropin surge in the male. The priming pheromones are relatively small molecules that are bound by urinary proteins, and are active at very low levels. Many mammals also have evolved specific behavior patterns for depositing pheromones. One of these involves “overmarking,” placing a scent so that it fully or partially overlaps that of a previous mark. Overmarking can be a form of competition between rivals for a territory or a mate. Moreover, identification of the vomeronasal organ as the receptor of priming pheromones ties these external chemical signals to the rich world of neurotransmitters in the central nervous system, and thus to endocrine changes in circulation that affect reproduction.
9 citations