J
John H. Fingert
Researcher at University of Iowa
Publications - 171
Citations - 14975
John H. Fingert is an academic researcher from University of Iowa. The author has contributed to research in topics: Glaucoma & Myocilin. The author has an hindex of 47, co-authored 165 publications receiving 13442 citations. Previous affiliations of John H. Fingert include University of Arkansas for Medical Sciences & University of Iowa Hospitals and Clinics.
Papers
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Journal ArticleDOI
Confirmation of the association between the TCF4 risk allele and Fuchs endothelial corneal dystrophy in patients from the Midwestern United States.
John F. Stamler,Ben R. Roos,Michael D. Wagoner,Kenneth M. Goins,Anna S. Kitzmann,Janet B. Riley,Edwin M. Stone,John H. Fingert +7 more
TL;DR: This study confirms the association between SNP rs613872 and FECD and shows that the TCF4 gene has an important role in the pathogenesis of corneal disease in patients from Iowa.
Journal ArticleDOI
The C677T variant in the methylenetetrahydrofolate reductase gene is not associated with disease in cohorts of pseudoexfoliation glaucoma and primary open-angle glaucoma patients from Iowa.
John H. Fingert,Young H. Kwon,Paula A. Moore,Rebecca M. Johnston,Kwang-Youn Kim,Val C. Sheffield,Wallace L.M. Alward,Edwin M. Stone +7 more
TL;DR: Elevated levels of homocysteine have been detected in the aqueous humor of patients with pseudoexfoliation glaucoma and hyperhomocysteinemia has been linked to vascular disease5,6 and homocy steine has been shown to induce apoptosis of retinal ganglion cells in a mouse model.
Journal ArticleDOI
novel Intragenic FRMD7 deletion in a Pedigree with congenital X-linked nystagmus
TL;DR: It is shown for the first time that large intragenic deletions of FRMD7 can also cause this form of nystagmus.
Patent
Diagnostics and therapeutics for glaucoma
TL;DR: In this article, the level of a Frizzle Related Protein (FRP), a component of the wingless (Wnt) signaling pathway, was determined for diagnosing and treating glaucoma.
Journal ArticleDOI
Familial Cavitary Optic Disk Anomalies: Identification of a Novel Genetic Locus
John H. Fingert,Robert Honkanen,Robert Honkanen,Suma P. Shankar,Louisa M. Affatigato,Mary A. Ehlinger,Michael D. Moore,Lee M. Jampol,Val C. Sheffield,Val C. Sheffield,Edwin M. Stone,Edwin M. Stone,Wallace L.M. Alward +12 more
TL;DR: The discovery of the chromosomal location of a gene responsible for cavitary optic disk anomalies is a key step in identifying the genetic basis of this condition and ultimately may provide important insight into the pathogenesis of more common optic nerve diseases such as normal-tension glaucoma and primary open-angle glAUcoma (POAG).