J
John H. Fingert
Researcher at University of Iowa
Publications - 171
Citations - 14975
John H. Fingert is an academic researcher from University of Iowa. The author has contributed to research in topics: Glaucoma & Myocilin. The author has an hindex of 47, co-authored 165 publications receiving 13442 citations. Previous affiliations of John H. Fingert include University of Arkansas for Medical Sciences & University of Iowa Hospitals and Clinics.
Papers
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Journal ArticleDOI
Genetics and genetic testing for glaucoma.
TL;DR: Genetic testing can serve as a powerful tool to improve diagnostic accuracy, efficiency of disease surveillance, and selection of treatment, enabling physicians to better optimize care for their patients.
Journal ArticleDOI
Case of Stargardt disease caused by uniparental isodisomy.
John H. Fingert,David A. Eliason,Nicole C. Phillips,Andrew J. Lotery,Val C. Sheffield,Edwin M. Stone +5 more
TL;DR: This work identified a patient affected with Stargardt disease who inherited 2 mutant alleles of the ABCA4 gene from her father throughamechanism known as uniparental disomy, which may result in expression of a recessive disease inherited from only 1 parent.
Journal Article
Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders.
TL;DR: It does not appear that major heritable risk alleles in these genes are responsible for the development of GC-induced ocular hypertension or POAG, and single nucleotide polymorphism genotyping shows no significant differences in allele frequencies or genotypes.
Journal ArticleDOI
Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.
Todd E. Scheetz,Ben Faga,Lizette Ortega,Ben R. Roos,Mae O. Gordon,Michael A. Kass,Kai Wang,John H. Fingert +7 more
TL;DR: The size of the OHTS cohort and its composition of 2 large racial subgroups may limit its power to detect some glaucoma risk factors, and the Cox proportional hazard analysis demonstrated that TMCO1 alleles increased relative risk comparable with that of some previously analyzed clinical measures.
Journal Article
Tank-Binding Kinase 1 ( TBK1 ) Gene and Open-Angle Glaucomas (An American Ophthalmological Society Thesis).
John H. Fingert,Alan L. Robin,Todd E. Scheetz,Young H. Kwon,Jeffrey M. Liebmann,Robert Ritch,Wallace L.M. Alward +6 more
TL;DR: A broader phenotypic range may be associated with TBK1 copy-number variations, although mutations in this gene are most often detected in patients with normal-tension glaucoma.