John McDaniel

TL;DR: Cold improved the subject's tolerance to LBNP, and was significantly lower throughout the COLD trial as compared to the AMB trials.

TL;DR: Evidence is provided that peripheral fatigue and associated afferent feedback limits the development of peripheral fatiguing and compromises endurance exercise performance by inhibiting CMD.

TL;DR: It is demonstrated that antioxidant consumption acutely restores endothelial function in the elderly while disrupting normal endothelium-dependent vasodilation in the young and suggested that this age-related impairment is attributed, at least in part, to free radicals.

TL;DR: It is concluded that endothelial NO synthase inhibition with L-NMMA abolishes the relationship between shear stress and BA vasodilation during handgrip exercise, providing clear evidence of NO-dependent vasodilating in this experimental model and support this paradigm as a novel and valid approach for a noninvasive assessment of No bioavailability in humans.

TL;DR: It is suggested that mechanical power output and pedal speed, a marker for muscle shortening velocity, are the main determinants of metabolic cost during submaximal cycling, whereas pedaling rate does not significantly contribute to metabolic cost.