J
John Potokar
Researcher at University of Bristol
Publications - 73
Citations - 2439
John Potokar is an academic researcher from University of Bristol. The author has contributed to research in topics: Anxiety & Anxiety disorder. The author has an hindex of 28, co-authored 73 publications receiving 2224 citations. Previous affiliations of John Potokar include Bristol Royal Infirmary & University Hospitals Bristol NHS Foundation Trust.
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Journal ArticleDOI
Serotonin reuptake inhibitor withdrawal
TL;DR: Reports of withdrawal symptoms in a retrospective chart review of 352 patients treated in an outpatient clinic with the nonselective serotonin reuptake inhibitor clomipramine or with one of the selective SSRIs, fluoxetine, fluvoxamine, paroxettine, or sertraline suggest a role has been suggested for serotonin in coordinating sensory and autonomic function with motor activity.
Journal ArticleDOI
Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study
Jon Nash,Peter A. Sargent,Eugenii A. Rabiner,Sean Hood,Spilios V. Argyropoulos,John Potokar,Paul M. Grasby,David J. Nutt +7 more
TL;DR: Panic disorder is associated with reduced 5-HT(1A) receptor availability, which is also known to have a key role in depression.
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Antidepressant-induced jitteriness/anxiety syndrome: systematic review
Lindsey I Sinclair,David M Christmas,Sean Hood,John Potokar,Andrea Robertson,Andrew Isaac,Shrikant Srivastava,David J. Nutt,Simon J. C. Davies +8 more
TL;DR: Jitteriness/anxiety syndrome remains poorly characterised and clinicians' perception of this syndrome influences prescribing and it is cited to support postulated mechanisms of drug action, but systematised evaluation of side-effects at earlier time points in antidepressant trials to further elucidate this clinically important syndrome.
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Predictive accuracy of risk scales following self-harm: Multicentre prospective cohort study
Leah Quinlivan,Jayne Cooper,Declan Meehan,D Longson,John Potokar,Tom Hulme,Jennifer Marsden,Fiona Brand,Kezia Lange,Elena Riseborough,Lisa Page,Chris Metcalfe,Linda Davies,Rory C. O'Connor,Keith Hawton,David Gunnell,Nav Kapur +16 more
TL;DR: In this paper, a multisite prospective cohort study was conducted of adults aged 18 years and over referred to liaison psychiatry services following self-harm and evaluated the performance of risk scales (Manchester Self-Harm Rule, ReACT Self Harm Rule, SAD PERSONS scale, Modified SAD Persons scale, Barratt Impulsiveness Scale, etc.).
Journal ArticleDOI
A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase
TL;DR: The use of immune-activated groups at high risk of depression have been used and found novel strategies for the future development of antidepressants including inhibition of indoleamine 2,3-dioxygenase, moderating the cytokines which activate it, or addressing other targets in the kynurenine pathway.