John Roote

TL;DR: Insertions from the collection now lie within or near most Drosophila genes, greatly reducing the time required to identify new mutations and analyze gene functions.

TL;DR: A collection of P-element insertions that have considerable utility for generating custom chromosomal aberrations in Drosophila melanogaster are described and their end points mapped, with base-pair resolution, to the genome sequence.

TL;DR: This work answers a longstanding question about the molecular nature of Minute loci and suggests that Minute phenotypes arise from suboptimal protein synthesis resulting from reduced levels of cytoribosomes.

TL;DR: The cloning of the first, to the authors' knowledge, Drosophila melanogaster gene involved in hybrid incompatibilities, Hybrid male rescue (Hmr) is reported, finding that Hmr encodes a protein with homology to a family of MYB-related DNA-binding transcriptional regulators.

TL;DR: The phenotypes of pk mutants, and transgenic flies in which the different isoforms are overexpressed show that the balance between Pk and Sple is critical for the specification of planar polarity, and suggest a tessellation model inwhich the alignment of wing hairs is dependent on cell shape and need not reflect fine-grained positional information.