John S. Thompson

TL;DR: It is found that total body irradiation (TBI) was essential to induce acute graft-versus-host disease (GVHD) after allogeneic H-2-incompatible splenocyte (SP) transplantation in SCID mice and significantly increased both serum and colonic tumor necrosis factor-alpha (TNF-alpha, interleukin-1 alpha, and IL-6 when compared with non-TBI regimens and normal controls.

TL;DR: A multi-centre, randomised trial was undertaken to determine the effects of ex-vivo T-cell depletion versus methotrexate and cyclosporine immunosuppression on 3-year disease-free survival.

TL;DR: Concern is raised about the use of whole blood from multiparous donors particularly when multiple transfusions must be administered after over five years had elapsed since the last pregnancy.

TL;DR: Results suggest that smoking‐induced alterations in NK activity may have a role in the pathogenesis of smoking‐associated carcinoma of the lung.

TL;DR: The findings suggest that de novo use of cyclosporine emulsion may simplify and improve management of organ transplant recipients and that the PK advantages of cyclOSporineEmulsion may translate into clinical benefits.