J
John S. Yu
Researcher at Cedars-Sinai Medical Center
Publications - 39
Citations - 1989
John S. Yu is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Neural stem cell & Neurosphere. The author has an hindex of 18, co-authored 39 publications receiving 1934 citations. Previous affiliations of John S. Yu include Harvard University.
Papers
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Journal ArticleDOI
Isolation of cancer stem cells from adult glioblastoma multiforme
Xiangpeng Yuan,James F. Curtin,Yizhi Xiong,Gentao Liu,Sebastian Waschsmann-Hogiu,Daniel L. Farkas,Keith L. Black,John S. Yu +7 more
TL;DR: The identification of tumor stem cells within adult GBM may represent a major step forward in understanding the origin and maintenance of GBM and lead to the identification and testing of new therapeutic targets.
Journal Article
Treatment of Glioma by Engineered Interleukin 4-secreting Cells
TL;DR: The absence of viable glioma cells as well as resolution of inflammation 19 days after treatment suggests the potential for complete tumor regression without ongoing inflammatory sequelae resulting from cytokine treatment.
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Isolation of tumour stem-like cells from benign tumours
Q Xu,Xiangpeng Yuan,Patrizia Tunici,Gentao Liu,X Fan,Minlin Xu,Jinwei Hu,Jae Youn Hwang,Daniel L. Farkas,Keith L. Black,John S. Yu +10 more
TL;DR: This study for the first time indicates that stem-like cells are present in benign tumours and demonstrated that PASCs are pituitary tumour-initiating cells in serial transplantation animal experiments.
Journal Article
Vaccination for experimental gliomas using GM-CSF-transduced glioma cells.
Ulrich Herrlinger,Christof M. Kramm,Karen M. Johnston,David N. Louis,Dianne M. Finkelstein,Reznikoff G,Dranoff G,Xandra O. Breakefield,John S. Yu +8 more
TL;DR: Subcutaneous injection of irradiated GM-CSF-transduced glioma cells can induce a potent immune response to intracranial gliomas both as a vaccination against subsequent intrac Cranial Glioma cell implantation and for treatment of established intrACranialglioma.
Journal ArticleDOI
Gene therapy for brain tumors
Christof M. Kramm,Miguel Sena-Esteves,F H Barnett,F H Barnett,Nikolai G. Rainov,Nikolai G. Rainov,Deborah E. Schuback,John S. Yu,Peter Pechan,Werner Paulus,Werner Paulus,E A Chiocca,Xandra O. Breakefield +12 more
TL;DR: Current gene therapy strategies and vector systems for treatment of brain tumors will be described and discussed in light of further developments needed to make this new treatment modality clinically efficacious.