J
John W. Griffin
Researcher at Johns Hopkins University
Publications - 292
Citations - 30661
John W. Griffin is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Axon & Neurofilament. The author has an hindex of 94, co-authored 292 publications receiving 29662 citations. Previous affiliations of John W. Griffin include Medical University of South Carolina & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
DNA/RNA Helicase Gene Mutations in a Form of Juvenile Amyotrophic Lateral Sclerosis (ALS4)
Ying Zhang Chen,Craig L. Bennett,Huy M. Huynh,Ian P. Blair,Imke Puls,Joy Irobi,Ines Dierick,Annette Abel,Marina L. Kennerson,Marina L. Kennerson,Bruce A. Rabin,Garth A. Nicholson,Garth A. Nicholson,Michaela Auer-Grumbach,Klaus Wagner,Peter De Jonghe,John W. Griffin,Kenneth H. Fischbeck,Vincent Timmerman,David R. Cornblath,Phillip F. Chance +20 more
TL;DR: Observations of ALS4 suggest that mutations in SETX may cause neuronal degeneration through dysfunction of the helicase activity or other steps in RNA processing.
Journal ArticleDOI
Guillain-Barré syndrome in northern China Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies
Tony W. Ho,Ban Mishu,C. Y. Li,C. Y. Gao,David R. Cornblath,John W. Griffin,Arthur K. Asbury,Martin J. Blaser,Martin J. Blaser,Guy M. McKhann +9 more
TL;DR: No statistically significant correlations were found between the pattern of disease, AMAN or AIDP, anti-glycolipid antibodies, or C. jejuni antibodies.
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Neurofilament gene expression: a major determinant of axonal caliber.
Paul N. Hoffman,Don W. Cleveland,John W. Griffin,Phillip W. Landes,Nicholas J. Cowan,Donald L. Price +5 more
TL;DR: The hypothesis that the expression of a single set of neuron-specific genes (encoding NF) directly determines axonal caliber is supported, a feature of neuronal morphology with important consequences for physiology and behavior.
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Acute motor axonal neuropathy : a frequent cause of acute flaccid paralysis in China
Guy M. McKhann,Guy M. McKhann,David R. Cornblath,John W. Griffin,Tony W. Ho,Tony W. Ho,C. Y. Li,Z. Jiang,Husheng Wu,G. Zhaori,Y. Liu,L. P. Jou,T. C. Liu,C. Y. Gao,J. Y. Mao,Martin J. Blaser,Ban Mishu,Arthur K. Asbury +17 more
TL;DR: It is established that this is a distinctive syndrome, distinguishable from poliomyelitis and demyelinating Guillain‐Barré syndrome, which is marked by rapidly progressive ascending tetraparesis, often with respiratory failure, but without fever, systemic illness, or sensory involvement.
Journal ArticleDOI
A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside.
Alan Pestronk,David R. Cornblath,Amjad A. Ilyas,H. Baba,Richard H. Quarles,John W. Griffin,K. Alderson,Robert N. Adams +7 more
TL;DR: 2 patients with a treatable, immune‐mediated motor polyneuropathy associated with antibodies to defined neural antigens, initially diagnosed as having lower motor neuron forms of amyotrophic lateral sclerosis are reported.