J
John W. Sumner
Researcher at Centers for Disease Control and Prevention
Publications - 67
Citations - 5808
John W. Sumner is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Ehrlichia chaffeensis & Ehrlichia. The author has an hindex of 41, co-authored 67 publications receiving 5551 citations. Previous affiliations of John W. Sumner include United States Department of Health and Human Services.
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Journal ArticleDOI
Rickettsia parkeri: A newly recognized cause of spotted fever rickettsiosis in the United States
Christopher D. Paddock,John W. Sumner,James A. Comer,Sherif R. Zaki,Cynthia S. Goldsmith,Jerome Goddard,Susan McLellan,Cynthia L. Tamminga,Christopher A. Ohl,Christopher A. Ohl +9 more
TL;DR: Disease in a human caused by Rickettsia parkeri is described, an SFG rickettsia first identified >60 years ago in Gulf Coast ticks collected from the southern United States, and application of specific laboratory assays to clinical specimens obtained from patients with febrile, eschar-associated illnesses following a tick bite may identify additional cases.
Journal ArticleDOI
Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis.
Richard S. Buller,Max Q. Arens,S P Hmiel,Christopher D. Paddock,John W. Sumner,Y Rikhisa,Ahmet Unver,Monique Gaudreault-Keener,Farrin A. Manian,Allison M. Liddell,Nathan Schmulewitz,Gregory A. Storch +11 more
TL;DR: Findings provide evidence of E. ewingii infection in humans and suggest that the associated disease may be clinically indistinguishable from infection caused by E. chaffeensis or the agent of human granulocytic ehrlichiosis.
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2009 Pandemic Influenza A (H1N1): Pathology and Pathogenesis of 100 Fatal Cases in the United States
Wun-Ju Shieh,Dianna M. Blau,Amy M. Denison,Marlene DeLeon-Carnes,Patricia Adem,Julu Bhatnagar,John W. Sumner,Lindy Liu,Mitesh Patel,Brigid Batten,Patricia W. Greer,Tara Jones,Chalanda Smith,Jeanine Bartlett,Jeltley L. Montague,Elizabeth White,Dominique Rollin,Rongbao Gao,Cynthia Seales,Heather Jost,Maureen G. Metcalfe,Cynthia S. Goldsmith,Charles D. Humphrey,Ann Schmitz,Clifton P. Drew,Christopher D. Paddock,Timothy M. Uyeki,Sherif R. Zaki +27 more
TL;DR: In this article, the most prominent histopathological feature observed was diffuse alveolar damage in the lung in all case-patients examined, including type I and type II pneumocytes, were the primary infected cells.
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PCR amplification and comparison of nucleotide sequences from the groESL heat shock operon of Ehrlichia species.
TL;DR: Degenerate PCR primers derived from conserved regions of the eubacterial groESL heat shock operon were used to amplifyGroESL sequences of Ehrlichia equi, EHRlichia phagocytophila, and the agent of human granulocytic ehrlichiosis, and a phylogenetic tree derived from deduced GroEL amino acid sequences was similar to trees based on 16S rRNA gene sequences.
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Detection of the etiologic agent of human ehrlichiosis by polymerase chain reaction.
Burt E. Anderson,John W. Sumner,J E Dawson,T Tzianabos,Cornelia R. Greene,James G. Olson,Daniel B. Fishbein,M Olsen-Rasmussen,Brian P. Holloway,E H George +9 more
TL;DR: PCR was applied to four ticks that were positive by direct immunofluorescence for Ehrlichia species, and one tick was PCR positive, indicating that E. chaffeensis DNA can be detected in ticks harboring this organism, although the sensitivity may be low.