J
Jolanta Weresa
Researcher at Medical University of Białystok
Publications - 11
Citations - 130
Jolanta Weresa is an academic researcher from Medical University of Białystok. The author has contributed to research in topics: Fatty acid amide hydrolase & Isoprenaline. The author has an hindex of 5, co-authored 10 publications receiving 84 citations.
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Journal ArticleDOI
Age-specific influences of chronic administration of the fatty acid amide hydrolase inhibitor URB597 on cardiovascular parameters and organ hypertrophy in DOCA-salt hypertensive rats
Marek Toczek,Marta Baranowska-Kuczko,Emilia Grzęda,Anna Pędzińska-Betiuk,Jolanta Weresa,Barbara Malinowska +5 more
TL;DR: Two weeks of URB597 administration to DOCA-salt hypertensive rats caused an age-specific reduction in BP, HR and cardiac and renal hypertrophy and did not affect the body weight, and water and food intake.
Journal ArticleDOI
Chronic inhibition of fatty acid amide hydrolase by URB597 produces differential effects on cardiac performance in normotensive and hypertensive rats.
Anna Pędzińska-Betiuk,Jolanta Weresa,Marek Toczek,Marta Baranowska-Kuczko,Irena Kasacka,Ewa Harasim-Symbor,Barbara Malinowska +6 more
TL;DR: Whether the potential hypotensive effect of chronic FAAH inhibition by URB597 in hypertensive rats correlated with changes in cardiac performance is examined.
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Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT3 Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats
TL;DR: Cannabidiol induces the Bezold-Jarisch reflex likely via TRPV1 receptors (which undergo tachyphylaxis) more markedly in SHR than in WKY and inhibits the BeZold-Garcia reflex induced by activation of 5-HT3 but not TRPv1 receptors; has peripheral sympathomimetic, vasodilatory, and negative inotropic effects.
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Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart.
Anna Pędzińska-Betiuk,Jolanta Weresa,Eberhard Schlicker,Ewa Harasim-Symbor,Marek Toczek,Irena Kasacka,Bernadetta Gajo,Barbara Malinowska +7 more
TL;DR: Cannabidiol has a modest beneficial effect in hypertension and its adverse effects in normotensive hearts, so caution should be taken when using CBD as a drug in therapy.
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The effects of chronic FAAH inhibition on myocardial lipid metabolism in normotensive and DOCA-salt hypertensive rats.
Agnieszka Polak,Ewa Harasim-Symbor,Barbara Malinowska,Irena Kasacka,Anna Pędzińska-Betiuk,Jolanta Weresa,Adrian Chabowski +6 more
TL;DR: It is revealed that chronic FAAH inhibition has no protective effects on the heart lipid metabolism in hypertension, and prolonged activation of the ECS in the normotensive rats induced cardiomyocyte enlargement and intensified fatty acids metabolism.