J
Jon Maakestad
Researcher at University of Iowa Hospitals and Clinics
Publications - 5
Citations - 170
Jon Maakestad is an academic researcher from University of Iowa Hospitals and Clinics. The author has contributed to research in topics: Hydroxychloroquine & Angiotensin-converting enzyme. The author has an hindex of 3, co-authored 5 publications receiving 134 citations. Previous affiliations of Jon Maakestad include University of Iowa.
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Journal ArticleDOI
Cross-reactivity of steroid hormone immunoassays: clinical significance and two-dimensional molecular similarity prediction
Matthew D. Krasowski,Denny Drees,Cory Morris,Jon Maakestad,John L Blau,John L Blau,Sean Ekins +6 more
TL;DR: Compounds producing cross-reactivity in steroid hormone immunoassays generally have a high degree of structural similarity to the target hormone, although interpretation is limited by sparse pharmacokinetic data for some of these drugs.
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Diagnostic pitfalls and laboratory test interference after hydroxychloroquine intoxication: A case report
TL;DR: Hydroxychloroquine overdose can cause hypokalemia and electrocardiographic abnormalities, and the drug can interfere with urine chemistry and drug screening assays.
Journal ArticleDOI
Ordering of the Serum Angiotensin-Converting Enzyme Test in Patients Receiving Angiotensin-Converting Enzyme Inhibitor Therapy: An Avoidable but Common Error
Matthew D. Krasowski,Johanna Savage,Alexandra Ehlers,Jon Maakestad,Gregory A. Schmidt,Sonia L. La'ulu,Natalie N. Rasmussen,Frederick G. Strathmann,Frederick G. Strathmann,Jonathan R. Genzen,Jonathan R. Genzen +10 more
TL;DR: Assessment of ACE activity is often measured for patients receiving ACEIs, potentially leading to low ACE concentrations and inaccurate interpretations, according to this study.
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Accidental intoxications in toddlers: lack of cross-reactivity of vilazodone and its urinary metabolite M17 with drug of abuse screening immunoassays.
Christina D. Martinez-Brokaw,Joshua B. Radke,Joshua G. Pierce,Alexandra Ehlers,Sean Ekins,Kelly E. Wood,Jon Maakestad,Jacqueline A. Rymer,Kenichi Tamama,Matthew D. Krasowski +9 more
TL;DR: While the vilazodone metabolite M17 has weak 2D structural similarity to amphetamines and tricyclic antidepressants, the current study did not demonstrate any experimental cross-reactivity with two different urine Amphetamines immunoassays and a serum tricycleclic antidepressant immunoASSay.
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Data on hydroxychloroquine interference with urine laboratory testing.
TL;DR: This case prompted a more detailed investigation of the effects of hydroxychloroquine spiked into pooled de-identified urine specimens from a hospital clinical laboratory, and the data provided provides the raw data for 24 urine assays that were investigated.