J
Jonathan J. Stott
Researcher at Harvard University
Publications - 18
Citations - 1582
Jonathan J. Stott is an academic researcher from Harvard University. The author has contributed to research in topics: Diffuse optical imaging & Optical tomography. The author has an hindex of 7, co-authored 18 publications receiving 1515 citations. Previous affiliations of Jonathan J. Stott include Massachusetts Institute of Technology.
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Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head
TL;DR: A novel Monte Carlo code for photon migration through 3D media with spatially varying optical properties, known as 'tMCimg', is described and can serve as a resource for solving the forward problem for complex 3D structural data obtained by MRI or CT.
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Tomographic optical breast imaging guided by three-dimensional mammography
Ang Li,Eric L. Miller,Misha E. Kilmer,Thomas J. Brukilacchio,Tina Chaves,Jonathan J. Stott,Quan Zhang,Tao Wu,MaryAnn Chorlton,Richard H. Moore,Daniel B. Kopans,David A. Boas +11 more
TL;DR: A modified Tikhonov regularization method is introduced to include three-dimensional x-ray mammography as a prior in the diffuse optical tomography reconstruction and an approach is suggested to find the optimal regularization parameters.
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Coregistered tomographic x-ray and optical breast imaging: initial results.
Quan Zhang,Thomas J. Brukilacchio,Ang Li,Jonathan J. Stott,Tina Chaves,Elizabeth M. C. Hillman,Tao Wu,MaryAnn Chorlton,Elizabeth A. Rafferty,Richard H. Moore,Daniel B. Kopans,David A. Boas +11 more
TL;DR: These results demonstrate that strictly coregistered x-ray and optical images enable a detailed comparison of the two images, which will ultimately lead to a better understanding of the relationship between the functional contrast afforded by optical imaging and the structural contrast provided byx-ray imaging.
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Volumetric diffuse optical tomography of brain activity.
TL;DR: These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light and a combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.
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Improved sensitivity to cerebral hemodynamics during brain activation with a time-gated optical system: analytical model and experimental validation
TL;DR: Time domain (TD) diffuse optical measurement systems are being applied to neuroimaging, where they can detect hemodynamics changes associated with cerebral activity and provide better depth sensitivity by gating late photons and rejecting early light, which is sensitive to the superficial physiological signal clutter.