J
Jonathan M. Ducore
Researcher at University of California, Davis
Publications - 90
Citations - 2505
Jonathan M. Ducore is an academic researcher from University of California, Davis. The author has contributed to research in topics: DNA damage & Haemophilia A. The author has an hindex of 22, co-authored 86 publications receiving 2230 citations. Previous affiliations of Jonathan M. Ducore include NewYork–Presbyterian Hospital & University of Louisville.
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Journal ArticleDOI
Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant.
Lindsey A. George,Spencer K. Sullivan,Adam Giermasz,John E.J. Rasko,John E.J. Rasko,Benjamin J. Samelson-Jones,Jonathan M. Ducore,Adam Cuker,Lisa M. Sullivan,Suvankar Majumdar,Jerome M. Teitel,Catherine E. McGuinn,Margaret V. Ragni,Alvin Luk,Daniel Hui,J. Fraser Wright,Yifeng Chen,Yun Liu,Katie Wachtel,Angela Winters,Stefan Tiefenbacher,Valder R. Arruda,Johannes C.M. Van der Loo,Olga Zelenaia,Daniel Takefman,Marcus E. Carr,Linda B. Couto,Xavier M. Anguela,Katherine A. High +28 more
TL;DR: Transgene‐derived factor IX coagulant activity enabled the termination of baseline prophylaxis and the near elimination of bleeding and factor use in 10 participants with hemophilia who received the same vectors.
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The North American Immune Tolerance Registry: practices, outcomes, outcome predictors.
Donna DiMichele,B. L. Kroner,S. Adair,J. Addiego,V. Anderson,Jorge Luiz Barbosa,P. Blatt,P. Bockenstedt,V. Castle,P. Chenaille,J. Cohen,E. Czapek,Jeffrey H. Davis,G. Davignon,P. De Alarcon,R. Dubowy,Jonathan M. Ducore,M. Dugdale,B. Ewenstein,J. Fahner,T. John Gribble,D. Gnarra,R. Gruppo,N. Hakami,M. Hanna,W. Hanna,P. Haut,G. Heggie,A. Homans,J. Hutter,C. Johnson,M. Kajani,M. Karpatkin,Casper Kasper,J. Katz,C. Kessler,Nigel S. Key,M. Koerper,B. Konkle,R. Kosinski,J. Lazerson,A. Lightsey,T. Loew,J. Lusher,W. MacLaughlin,M. Manco-Johnson,C. Manno,K. McRedmond,P. Phatak,Jerry S. Powell,M. Ragni,C. Rosenfield,J. Sanders,P. Santiago-Borrero,P. Saidi,R. Seeler,S. Seremetis,J. Sexauer,S. Travis,L. Valdez,E. Warner,G. White,D. Barrand,J. Drown,J. Herst,M. Inwood,D. Lillicrap,G. Rivard,S. Rubin,H. Stranczyniski,J. Teitel +70 more
TL;DR: Outcome predictors were not evaluable for HB, although adverse reactions to therapy, including nephrotic syndrome, and access complications were more common among failed courses, and infection most often complicated the use of access catheters.
Journal ArticleDOI
DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas.
TL;DR: Normal (IMR-90) and simian virus 40-transformed human embryo cells were treated with antitumor nitrosoureas, and the effects on cell viability and cell DNA were compared, suggesting a possible difference in DNA repair between the cell lines.
Journal ArticleDOI
Bone pain as an initial symptom of childhood acute lymphoblastic leukemia: Association with nearly normal hematologic indexes
TL;DR: It is concluded that children with acute lymphoblastic leukemia who have prominent bone pain preceding the diagnosis frequently have nearly normal hematologic values and that this feature may contribute to a delay in diagnosis.
Journal ArticleDOI
INDUCTION OF DNA STRAND BREAKS IN NORMAL HUMAN FIBROBLASTS EXPOSED TO MONOCHROMATIC ULTRAVIOLET AND VISIBLE WAVELENGTHS IN THE 240–546 nm RANGE
TL;DR: The action spectrum for DNA strand breakage was found to exhibit one peak at 265 nm, consistent with DNA absorption, and a second peak at 450 nm, similar to the normalized absorption spectrum for riboflavin, a known photosensitizing agent, implicating this molecule as the absorbing chromophore.