Showing papers in "The Journal of Pediatrics in 1990"

TL;DR: Prenatal exposure to polychlorinated biphenyls and related contaminants predicted poorer short-term memory function on both verbal and quantitative tests in a dose-dependent fashion and demonstrates the continuation of a toxic impact received in utero and observed initially during infancy on a dimension of cognitive functioning fundamental to learning.

TL;DR: Skin test results were positive in most children with a positive DBPCFC reaction, but the large number of patients with asymptomatic hypersensitivity limited the accuracy of a positive skin test result alone as a predictor of clinical symptoms during food ingestion.

TL;DR: It is concluded that although P. aeruginosa colonization is associated with 10% lower lung function, it does not cause an immediate and rapid reduction, as has been previously reported.

TL;DR: It is concluded that platelet activating factor and TNF-alpha are elevated in patients with necrotizing enterocolitis and that suppressed platelets activating factor degradation contributes to the increased platelet activates factor levels.

TL;DR: Although a broad array of sociodemographic factors correlated with school difficulty, very low birth weight and hyperactivity scores contributed independently to the risk of academic problems.

TL;DR: An outbreak of Escherichia coli O175:H7 infection resulting in a high rate of progression to hemolytic-uremic syndrome is described, and predictors of and risk factors for progression are identified.

TL;DR: The observed MAP changes in those with PV-IVH lend support to a significant role for MAP alterations in the pathogenesis of PV-IIIH, as well as to a greater percentage of time, than their matched control subjects spent.

TL;DR: Overall, coagulation necrosis was more severe than any other finding in most infants, indicating the importance of ischemia in the pathophysiology of necrotizing enterocolitis.

TL;DR: Exclusion of cow milk from the diet of infants and young children with cow milk allergy did not prevent the subsequent development of atopic disorders, and it is unclear whether independent mechanisms control the development ofCow milk allergy and other atopic conditions.

TL;DR: A satisfactory initial outcome shows the feasibility and potential of this treatment of pulmonary dysfunction in the preterm neonate.

TL;DR: To prevent problems in feeding, practitioners may teach and support positive feeding dynamics as part of primary care, refer parents for instruction in positive approaches to feeding, and detect and refer attitudinal and behavioral problems early.

TL;DR: It is concluded that abolished autoregulation is associated with cerebral damage in asphyxiated infants and that the combination of isoelectric electroencephalograms and cerebral hyperperfusion is an early indicator of very severe brain damage.

TL;DR: It is concluded that early postnatal dexamethasone therapy improves pulmonary status, facilitates removal of the endotracheal tube, and minimizes lung injuries in premature infants with severe respiratory distress syndrome.

TL;DR: Experience with 3327 teenagers demonstrated that 89% preferred the computer over a questionnaire or personal interview, but nearly all were willing to share the printout with the pediatrician, which should facilitate clinical evaluation.

TL;DR: The effects of social learning on body mass index, indicated by parental educational level, appear to strengthen over time, whereas the effects of the vigorous feeding style wane.

TL;DR: The ability to defecate balloons is apparently not dependent on the normal function of the external and sphincter and pelvic floor muscles alone, and biofeedback treatment is complementary to a good conventional therapeutic regimen in patients with abnormal defecation dynamics.

TL;DR: In this paper, the authors investigated whether this resistance can be overcome by administration of recombinant human growth hormone in supraphysiologic doses in children with severe uremia.

TL;DR: The results suggest that the cortisol production rate in children and adolescents is significantly lower than previously estimated.

TL;DR: The finding that A-subtype infections were more severe than B-sub type infections among the 157 infants hospitalized in two hospitals in Rochester, N.Y., during two winters might have important implications for vaccine development, studies of the virulence of respiratory syncytial virus, clinical management, and long-term prognosis.

TL;DR: It is concluded that the very small infants now dying in nurseries have a form of white matter damage that is more extensive than, and in some cases histologically different from, periventricular leukomalacia as originally described.

TL;DR: An association between Campylobacter antibodies in human milk and prevention of diarrhea caused by Campyloblacter jejuni is shown.

TL;DR: Evidence is provided that acyclovir is useful and well tolerated for treatment of varicella in otherwise healthy children.

TL;DR: It is concluded that failure of the sodium concentration measured in serum to rise as glucose concentration declines is a marker for excessive administration of free water and an expanded repair period, with repair fluid containing an average of 125 mmol/L Na+ early in therapy, will protect against a downward trend in the concentration of sodium in serum and therefore against a rapid decline in effective serum osmolality.

TL;DR: The hypothesis that the incidence of NEC is significantly reduced after prenatal steroid treatment is supported and postnatal therapy with steroids does not decrease the incidence as effectively as prenatal therapy, it improves clinical outcome of NEC.

TL;DR: Maximal amounts of expired ethane and pentane were significantly higher for patients with a poor outcome than for those with good outcome, implying a role for free oxygen radicals in the pathogenesis of life-threatening complications in the very low birth weight infant.

TL;DR: Serum iron and ferritin levels rapidly decreased after the initiation of rHuEpo therapy, and in most patients transient early thrombocytosis and late neutropenia were observed, suggesting that r HuEpo may correct or stabilize the anemia of prematurity.

TL;DR: The results suggest that the great majority of children who have a febrile seizure do not need anticonvulsant treatment even if one of the factors listed in the Consensus Statement is present, and that the rationale and indications for treating febRIle seizures need to be reconsidered.

TL;DR: Serum drug concentrations may need to be monitored in high-risk, low birth weight infants and the dose of amphotericin B given on the first day of treatment should be greater than the usual testing dose of 0.1 mg/kg/day.

TL;DR: Among 19,044 children born to mothers with monitored pregnancies and followed medically for at least 5 years, 41 (0.2%) had cerebral palsy that was not the result of a progressive disease or of a neural tube defect.