J
Jonathan M. Solomon
Publications - 4
Citations - 475
Jonathan M. Solomon is an academic researcher. The author has contributed to research in topics: Acetylation & DNA damage. The author has an hindex of 3, co-authored 4 publications receiving 442 citations.
Papers
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Journal ArticleDOI
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.
Jonathan M. Solomon,Rao Pasupuleti,Lei Xu,Thomas McDonagh,Rory A. J. Curtis,Peter S. DiStefano,L. Julie Huber +6 more
TL;DR: Results show that, although SIRT1 deacetylates p53, this does not play a role in cell survival following DNA damage in certain cell lines and primary human mammary epithelial cells.
Patent
Methods of treating disorder
Andrew Napper,Peter Distefano,Jeffrey Hixon,Thomas McDonagh,Jonathan M. Solomon,L. Julie Huber,Rory A. J. Curtis,Russell J. Thomas,Jean-François Pons +8 more
TL;DR: In this article, a compound of formula (I) and methods of treating disorders by administering a compound-of-formula(I) are described, including neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
Patent
SirT INHIBITORS THAT BIND TO NAD
Andrew Napper,Peter S. DiStefano,Rory A. J. Curtis,Jeffrey Hixon,Thomas McDonagh,L. Julie Huber,Jonathan M. Solomon,Russell J. Thomas,Jean-François Pons +8 more
TL;DR: In this paper, a compound of formula (I) and methods of treating disorders by administering a compound-of-formula(I) are described, examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.