Jong-Il Park

TL;DR: Results show that, in addition to apoptosis, DHA increased the expression levels of lipidated form LC3B and potently stimulated the autophagic flux, suggesting that DHA induces both autophagy and apoptosis in cancer cells expressing mutant p53.

TL;DR: The results suggest that PL has a direct antitumor effect through apoptosis and cell cycle blockade in certain cancer cells.

TL;DR: The role of DJ-1 in complex I formation is investigated by using blue native-polyacrylamide gel electrophoresis and 2-dimensional gel analysis to assess native complex status and it is concluded thatDJ-1 null cells have a defect in the assembly of complex I, a pathological mechanism for the degeneration of dopaminergic neurons in Parkinson's disease.

TL;DR: In this article, the relationship between ω3-PUFAs and β-catenin, one of the key determinants of anticancer properties, was investigated. But the relationship was not shown to be causal.

TL;DR: Data suggest that DHA-induced apoptosis and autophagy in NSCLC cells are associated with AMPK activation and PI3K/Akt inhibition, which in turn lead to suppression of mTOR; thus ω3-PUFAs may be utilized as potential therapeutic agents for NSCLc treatment.