J
Jong-Seok Kim
Researcher at Konyang University
Publications - 15
Citations - 177
Jong-Seok Kim is an academic researcher from Konyang University. The author has contributed to research in topics: Neuroprotection & Amyloid beta. The author has an hindex of 5, co-authored 15 publications receiving 64 citations.
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Journal ArticleDOI
Red Ginseng Attenuates Aβ-Induced Mitochondrial Dysfunction and Aβ-mediated Pathology in an Animal Model of Alzheimer's Disease
Soo Jung Shin,Seong Gak Jeon,Jin-il Kim,Yu-on Jeong,Sujin Kim,Yong Ho Park,Seong-kyung Lee,Hyun Ha Park,Sang Bum Hong,Sua Oh,Ji-Young Hwang,Hyeon soo Kim,HyunHee Park,Yunkwon Nam,Yong Yook Lee,Jwa-Jin Kim,Sun-Hyun Park,Jong-Seok Kim,Minho Moon +18 more
TL;DR: In vitro and in vivo findings indicated that RGE significantly improves Aβ-induced mitochondrial pathology and significantly ameliorated AD-related pathology, such as Aβ deposition, gliosis, and neuronal loss, and deficits in adult hippocampal neurogenesis in brains with AD.
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Omega-3 Fatty Acid-Type Docosahexaenoic Acid Protects against Aβ-Mediated Mitochondrial Deficits and Pathomechanisms in Alzheimer's Disease-Related Animal Model.
Yong Ho Park,Soo Jung Shin,Hyeon soo Kim,Sang Bum Hong,Sujin Kim,Yunkwon Nam,Jwa-Jin Kim,Kyu Lim,Jong-Seok Kim,Jin-il Kim,Seong Gak Jeon,Seong Gak Jeon,Minho Moon +12 more
TL;DR: In vitro and in vivo findings demonstrate that DHA attenuated AD-associated pathologies, such as mitochondrial impairment, Aβ accumulation, neuroinflammation, neuronal loss, and impairment of adult hippocampal neurogenesis.
Journal ArticleDOI
Therapeutic effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on aging and Alzheimer's disease.
Soo Jung Shin,Yunkwon Nam,Yong Ho Park,Min-Jeong Kim,Eunbeen Lee,Seong Gak Jeon,Bong-Seok Bae,Jiho Seo,Sung-Lye Shim,Jong-Seok Kim,Chang-Kyun Han,Sujin Kim,Yong Yook Lee,Minho Moon +13 more
TL;DR: Wang et al. as mentioned in this paper investigated the effects of NFP from Korean red ginseng (KRG) on AD pathologies, such as Aβ deposition, neuroinflammation, neurodegeneration, mitochondrial dysfunction, and impaired adult hippocampal neurogenesis.
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mTOR-Dependent Role of Sestrin2 in Regulating Tumor Progression of Human Endometrial Cancer.
Jiha Shin,Jeongyun Bae,Sumi Park,Hyun-Goo Kang,Seong Min Shin,Gunho Won,Gunho Won,Jong-Seok Kim,Ssang-Goo Cho,Youngsok Choi,Sang-Muk Oh,Jongdae Shin,Jeong Sig Kim,Hwan-Woo Park +13 more
TL;DR: Upregulation of SESN2 statistically correlated with shorter overall survival and disease-free survival in patients with endometrial cancer, and a relationship between S ESN2, the mTORC1 pathway, and endometri cancer growth, suggesting SESn2 as a potential therapeutic target in endometrian cancer.
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Targeting TBK1 Attenuates LPS-Induced NLRP3 Inflammasome Activation by Regulating of mTORC1 Pathways in Trophoblasts.
TL;DR: In this paper, the effect of TBK1 inhibition on lipopolysaccharide (LPS)-induced NLRP3 inflammasome activation and its underlying mechanisms in human trophoblast cell lines and mouse placenta was investigated.