Jongoh Shin

TL;DR: Using the nanopore sequencing platform to sequence full-length 16S rRNA amplicon libraries prepared from the mouse gut microbiota will be useful for rapid, accurate and efficient detection of microbial diversity in various biological and clinical samples.

TL;DR: Methods to increase the productivity and yield/titer scan by controlling metabolic flux through individual or combinatorial use of CRISPR/Cas andCRISPRi systems with introduction of synthetic pathway in industrially common bacteria including Escherichia coli are focused on.

TL;DR: Min content in the growth medium plays a critical role in the improvement by A. muciniphila of high-fat diet-induced obesity, intestinal inflammation, and compromised intestinal barrier integrity related to a decrease in goblet cell density.

TL;DR: It is discovered that the WLP and the glycine synthase pathway are functionally interconnected to fix CO2, subsequently converting CO2 into acetyl-CoA, acetyl -phosphate, and serine, which is a unique coutilization of the pathways under autotrophic conditions in acetogens.

TL;DR: Comparison of acetogenic bacterial genomes revealed that most genes in the acetogen-specific core genome were associated with the Wood-Ljungdahl pathway, a central metabolic pathway, and cofactor biosynthetic pathways are highly conserved for autotrophic growth.