J
Joon-Hee Lee
Researcher at Gyeongsang National University
Publications - 29
Citations - 820
Joon-Hee Lee is an academic researcher from Gyeongsang National University. The author has contributed to research in topics: Somatic cell nuclear transfer & Blastocyst. The author has an hindex of 13, co-authored 28 publications receiving 762 citations. Previous affiliations of Joon-Hee Lee include Kangwon National University & University of Nottingham.
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Journal ArticleDOI
Somatic cell nuclear transfer: Past, present and future perspectives.
Keith H.S. Campbell,Pat Fisher,Wenchao Chen,Inchul Choi,Richard Kelly,Joon-Hee Lee,Joon-Hee Lee,J Xhu +7 more
TL;DR: The process of animal production by nuclear transfer is discussed and in particular changes in the methodology which have increased development and survival, simplified or increased robustness of the technique are discussed.
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Cloning: eight years after Dolly.
Keith H.S. Campbell,Ramiro Alberio,Inchul Choi,Pat Fisher,Richard Kelly,Joon-Hee Lee,Walid E. Maalouf +6 more
TL;DR: The objectives of this paper are to review some of the successes and failures of the nuclear transfer procedure since the production of Dolly, and discuss studies from the laboratory and others which have modified the procedure in ways which may impact on development.
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Effects of enucleation and caffeine on maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) activities in ovine oocytes used as recipient cytoplasts for nuclear transfer
Joon-Hee Lee,Keith H.S. Campbell +1 more
TL;DR: The results show that caffeine can increase MPF and MAPK activities in ovine oocytes and that this may contribute to an increased reprogramming in NT embryos.
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Aberrant nucleo-cytoplasmic cross-talk results in donor cell mtDNA persistence in cloned embryos.
Rhiannon E. Lloyd,Joon-Hee Lee,Ramiro Alberio,Emma J. Bowles,João Ramalho-Santos,Keith H.S. Campbell,Justin C. St. John +6 more
TL;DR: In nuclear transfer-derived embryos, it is evident from the donor cells used that nuclear-encoded mitochondrial DNA transcription and replication factors persist even after mitochondrial DNA depletion, as do transcripts for some of the mitochondrial-encoding genes.
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Contrasting Effects of in Vitro Fertilization and Nuclear Transfer on the Expression of mtDNA Replication Factors
Emma J. Bowles,Joon-Hee Lee,Ramiro Alberio,Rhiannon E. Lloyd,Dov J. Stekel,Keith H.S. Campbell,Justin C. St. John +6 more
TL;DR: To account for the persistence of donor cell mtDNA, even when introduced at residual levels (mtDNAR), it was hypothesized that POLG and TFAM would be upregulated in intra- and interspecific and intergeneric NT embryos when compared to in vitro fertilized (IVF) embryos.