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Jorge Perez

Researcher at University of Milan

Publications -  108
Citations -  7637

Jorge Perez is an academic researcher from University of Milan. The author has contributed to research in topics: Protein kinase A & Fluvoxamine. The author has an hindex of 43, co-authored 107 publications receiving 7322 citations. Previous affiliations of Jorge Perez include University of Brescia & Università telematica San Raffaele.

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Journal Article

Functional atlas of emotional faces processing: a voxel-based meta-analysis of 105 functional magnetic resonance imaging studies.

TL;DR: This study has detailed neurofunctional maps to use as normative references in future fMRI studies of emotional facial processing in psychiatric populations, and found selective differences between neural networks underlying the basic emotions in limbic and insular brain regions.
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Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine.

TL;DR: Genotyping at 5-HTT promoter may represent a promising tool to individualize the pharmacological treatment of depression and seems to be related to fluvoxamine efficacy in delusional depression.
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GABAergic dysfunction in mood disorders

TL;DR: The hypothesis of reduced GABAergic activity in mood disorders may complement the monoaminergic and serotonergic theories, proposing that the balance between multiple neurotransmitter systems may be altered in these disorders.
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Signaling Pathways Regulating Gene Expression, Neuroplasticity, and Neurotrophic Mechanisms in the Action of Antidepressants: A Critical Overview

TL;DR: The available evidence is reviewed with an attempt to identify the reasons for experimental discrepancies and possible directions for future research into the regulation of brain-derived neurotrophic factor, a CREB-regulated gene, which has been implicated in both the pathophysiology and pharmacology of mood disorders.
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Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis.

TL;DR: Relatives of patients affected with psychosis, the co-twins of patients and subjects with an At Risk Mental State appear to share similar neurocognitive abnormalities that are qualitatively similar but less severe than those observed in the first episode of illness.