J
Jose Cortinas-Abrahantes
Researcher at European Food Safety Authority
Publications - 1
Citations - 50
Jose Cortinas-Abrahantes is an academic researcher from European Food Safety Authority. The author has an hindex of 1, co-authored 1 publications receiving 31 citations.
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Investigating combined toxicity of binary mixtures in bees: Meta-analysis of laboratory tests, modelling, mechanistic basis and implications for risk assessment.
Edoardo Carnesecchi,Claus Svendsen,Stefano Lasagni,Audrey Grech,Nadia Quignot,Billy Amzal,Cosimo Toma,Simone Tosi,Agnès Rortais,Jose Cortinas-Abrahantes,Ettore Capri,Nynke I. Kramer,Emilio Benfenati,David J. Spurgeon,Gilles Guillot,Jean Lou Dorne,Jean Lou Dorne +16 more
TL;DR: The mechanisms behind such synergistic effects of binary mixtures in bees are known to involve direct cytochrome P450 (CYP) inhibition, resulting in an increase in internal dose and toxicity of the binary mixture, which is known to have the lowest number of CYP copies and other detoxification enzymes in the insect kingdom.