Josefina Coloma

TL;DR: DENV2 nonstructural protein 3-specific immunostaining supports roles for infected phagocytes, hepatocytes, and, to a limited degree, endothelial cells in the pathogenesis of severe dengue.

TL;DR: Evidence based community mobilization can add effectiveness to dengue vector control as each site implementing the intervention in its own way has the advantage of local customization and strong community engagement.

TL;DR: This large-scale cohort study of dengue in the Americas demonstrates year-to-year variation of d Dengue within a pediatric population, revealing expected patterns in transmission while highlighting the impact of interventions, climate, and viral evolution.

TL;DR: Current knowledge and recent insights into dengue epidemiology, immunology, and pathogenesis, and their implications for understanding natural infection and current and future vaccines are summarized.

TL;DR: This study investigated prospective pediatric cohorts in Nicaragua that experienced sequential DENV1 to -3, Zika (2004 to 2015), Zika (2016 to 2017), and DENV2 (2018 to 2020) epidemics and found that prior immunity to Zika virus increases the risk of severe dengue disease via cross-reacting antibodies.