E
Edward C. Holmes
Researcher at University of Sydney
Publications - 894
Citations - 105137
Edward C. Holmes is an academic researcher from University of Sydney. The author has contributed to research in topics: Virus & Population. The author has an hindex of 138, co-authored 824 publications receiving 85748 citations. Previous affiliations of Edward C. Holmes include Imperial College London & Armed Forces Institute of Pathology.
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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
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A new coronavirus associated with human respiratory disease in China.
Fan Wu,Su Zhao,Bin Yu,Yan-Mei Chen,Wen Wang,Zhi gang Song,Yi Hu,Zhao Wu Tao,Jun Hua Tian,Yuan Yuan Pei,Ming Li Yuan,Yu Ling Zhang,Fa Hui Dai,Yi Liu,Qi Min Wang,Jiao Jiao Zheng,Lin Xu,Edward C. Holmes,Edward C. Holmes,Yong-Zhen Zhang,Yong-Zhen Zhang +20 more
TL;DR: Phylogenetic and metagenomic analyses of the complete viral genome of a new coronavirus from the family Coronaviridae reveal that the virus is closely related to a group of SARS-like coronaviruses found in bats in China.
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The proximal origin of SARS-CoV-2.
Kristian G. Andersen,Kristian G. Andersen,Andrew Rambaut,W. Ian Lipkin,Edward C. Holmes,Robert F. Garry +5 more
TL;DR: It is shown that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus, and scenarios by which they could have arisen are discussed.
Journal ArticleDOI
A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology.
Andrew Rambaut,Edward C. Holmes,Áine O'Toole,Verity Hill,John T. McCrone,Christopher Ruis,Louis du Plessis,Oliver G. Pybus +7 more
TL;DR: A rational and dynamic virus nomenclature that uses a phylogenetic framework to identify those lineages that contribute most to active spread and is designed to provide a real-time bird’s-eye view of the diversity of the hundreds of thousands of genome sequences collected worldwide.
Journal ArticleDOI
A Metagenomic Survey of Microbes in Honey Bee Colony Collapse Disorder
Diana Cox-Foster,Sean Conlan,Edward C. Holmes,Edward C. Holmes,Gustavo Palacios,Jay D. Evans,Nancy A. Moran,Phenix Lan Quan,Thomas Briese,Mady Hornig,David M. Geiser,Vince Martinson,Dennis vanEngelsdorp,Dennis vanEngelsdorp,Abby L. Kalkstein,Andrew T. Drysdale,Jeffrey Hui,Junhui Zhai,Liwang Cui,Stephen K. Hutchison,Jan Fredrik Simons,Michael Egholm,Jeffery S. Pettis,W. Ian Lipkin +23 more
TL;DR: The observation that irradiated combs from affected colonies can be repopulated with naive bees suggests that infection may contribute to colony collapse disorder (CCD).