J
Josep R. Ticó
Researcher at University of Barcelona
Publications - 34
Citations - 844
Josep R. Ticó is an academic researcher from University of Barcelona. The author has contributed to research in topics: Solid lipid nanoparticle & Particle size. The author has an hindex of 16, co-authored 33 publications receiving 687 citations.
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Journal ArticleDOI
Impact of physical parameters on particle size and reaction yield when using the ionic gelation method to obtain cationic polymeric chitosan-tripolyphosphate nanoparticles.
Anna Fàbregas,Montserrat Miñarro,Encarna García-Montoya,Pilar Pérez-Lozano,Carolina Carrillo,Rocío Sarrate,N. Sánchez,Josep R. Ticó,Josep M. Suñé-Negre +8 more
TL;DR: The results indicate that stirring speed during ionic gelation reaction is decisive for the size of the nanoparticles obtained, and therefore, by manipulating this parameter a greater proportion of nanoparticles of a given size range can be obtained.
Journal ArticleDOI
A new expert systems (SeDeM diagram) for control batch powder formulation and preformulation drug products.
Pilar Pérez,Josep M. Suñé-Negre,Montserrat Miñarro,Manel Roig,Roser Fuster,Encarna García-Montoya,Carmen Hernández,Ramon Ruhí,Josep R. Ticó +8 more
TL;DR: It was concluded that the SeDeM Method is suitable for testing batch-to-batch reproducibility of characteristics in powdered APIs substances and is a useful, effective tool for drug-preformulation studies providing the pharmacotechnical data required when formulating a drug in tablet form.
Journal ArticleDOI
Application of the SeDeM Diagram and a new mathematical equation in the design of direct compression tablet formulation.
Josep M. Suñé-Negre,Pilar Pérez-Lozano,Montserrat Miñarro,Manel Roig,Roser Fuster,Carmen Hernández,Ramon Ruhí,Encarna García-Montoya,Josep R. Ticó +8 more
TL;DR: The results obtained confirm that the SeDeM Method is an appropriate system, effective tool for determining a viable formulation for tablets prepared by direct compression, and can thus be used as the basis for the relevant pharmaceutical development.
Journal ArticleDOI
Quality by Design approach to understand the physicochemical phenomena involved in controlled release of captopril SR matrix tablets.
J. Saurí,D. Millán,Josep M. Suñé-Negre,Helena Colom,Josep R. Ticó,Montserrat Miñarro,Pilar Pérez-Lozano,Encarna García-Montoya +7 more
TL;DR: The size of water-filled pores and the degree of crosslinking between the chains of HPMC K15M of the matrix are related to the exponent n of the Korsmeyer-Peppas equation and the type of transport of the captopril from within the matrix to the dissolution medium is shown.
Journal ArticleDOI
Formulation of Direct Compression Zidovudine Tablets to Correlate the SeDeM Diagram Expert System and the Rotary Press Simulator Styl'ONE Results.
Isaac Nofrerias,Anna Nardi,Marc Suñé-Pou,Marc Suñé-Pou,Josep M. Suñé-Negre,Encarna García-Montoya,Pilar Pérez-Lozano,Montserrat Miñarro,Bernard Bataille,Josep R. Ticó +9 more
TL;DR: The SeDeM diagram expert system has been applied to study Zidovudine and some excipients and indicates that the formulation is able to be compressed adequately with the emulated compression profiles and no differences are observed between the final products.