J
Joseph Itskovitz-Eldor
Researcher at Technion – Israel Institute of Technology
Publications - 212
Citations - 39836
Joseph Itskovitz-Eldor is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 60, co-authored 212 publications receiving 38298 citations. Previous affiliations of Joseph Itskovitz-Eldor include Rappaport Faculty of Medicine & Rambam Health Care Campus.
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Journal ArticleDOI
Embryonic Stem Cell Lines Derived from Human Blastocysts
James A. Thomson,Joseph Itskovitz-Eldor,Sander S. Shapiro,Michelle A. Waknitz,Swiergiel Jennifer J,Vivienne S. Marshall,Jeffrey M. Jones +6 more
TL;DR: Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes, express high levels of telomerase activity, and express cell surface markers that characterize primate embryonic stem cells but do not characterize other early lineages.
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Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes.
Izhak Kehat,Dorit Kenyagin-Karsenti,Mirit Snir,Hana Segev,Michal Amit,Amira Gepstein,Erella Livne,Ofer Binah,Joseph Itskovitz-Eldor,Lior Gepstein +9 more
TL;DR: The human ES cell--derived cardiomyocytes displayed structural and functional properties of early-stage cardiomers, which may have significant impact on the study of early human cardiac differentiation, functional genomics, pharmacological testing, cell therapy, and tissue engineering.
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Clonally Derived Human Embryonic Stem Cell Lines Maintain Pluripotency and Proliferative Potential for Prolonged Periods of Culture
Michal Amit,Melissa K. Carpenter,Margaret S. Inokuma,Choy-Pik Chiu,Charles P. Harris,Michelle A. Waknitz,Joseph Itskovitz-Eldor,James A. Thomson +7 more
TL;DR: The clonal derivation of two human ES cell lines, H9.1 and H.2, demonstrates the pluripotency of single human ES cells, the maintenance of pluripOTency during an extended period of culture, and the long-term self-renewing properties of cultured human ES Cells.
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Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers.
Joseph Itskovitz-Eldor,Maya Schuldiner,Dorit Karsenti,Amir Eden,Ofra Yanuka,Michal Amit,Hermona Soreq,Nissim Benvenisty +7 more
TL;DR: The ability to induce formation of human embryoid bodies that contain cells of neuronal, hematopoietic and cardiac origins will be useful in studying early human embryonic development as well as in transplantation medicine.
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Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
TL;DR: This analysis sets the stage for directing differentiation of human ES cells in culture and indicates that multiple human cell types may be enriched in vitro by specific factors.