J
Joseph L. Price
Researcher at Washington University in St. Louis
Publications - 165
Citations - 55130
Joseph L. Price is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Cortex (anatomy) & Prefrontal cortex. The author has an hindex of 98, co-authored 162 publications receiving 52630 citations. Previous affiliations of Joseph L. Price include Johns Hopkins University & Salk Institute for Biological Studies.
Papers
More filters
Journal ArticleDOI
Subgenual prefrontal cortex abnormalities in mood disorders
Wayne C. Drevets,Joseph L. Price,Joseph R. Simpson,Richard D. Todd,Theodore Reich,Michael W. Vannier,Michael W. Vannier,Marcus E. Raichle +7 more
TL;DR: Using positron emission tomographic images of cerebral blood flow and rate of glucose metabolism to measure brain activity, an area of abnormally decreased activity is localized in the pre-frontal cortex ventral to the genu of the corpus callosum in both familial bipolar depressives and familial unipolar depressives.
Journal ArticleDOI
The Organization of Networks within the Orbital and Medial Prefrontal Cortex of Rats, Monkeys and Humans
Dost Öngür,Joseph L. Price +1 more
TL;DR: The OMPFC appears to function as a sensory-visceromotor link, especially for eating, which appears to be critical for the guidance of reward-related behavior and for setting of mood.
Journal ArticleDOI
Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression
TL;DR: Because the MPFC and related limbic structures provide forebrain modulation over visceral control structures in the hypothalamus and brainstem, their dysfunction can account for the disturbances in autonomic regulation and neuroendocrine responses that are associated with mood disorders.
Journal ArticleDOI
Mild cognitive impairment represents early-stage Alzheimer disease.
John C. Morris,Martha Storandt,J. Phillip Miller,Daniel W. McKeel,Joseph L. Price,Eugene H. Rubin,Leonard H. van den Berg +6 more
TL;DR: It is concluded that MCI generally represents early-stage AD and individuals currently characterized as having MCI progress steadily to greater stages of dementia severity at rates dependent on the level of cognitive impairment at entry and they almost always have the neuropathologic features of AD.
Journal ArticleDOI
Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease
Teresa Gomez-Isla,Joseph L. Price,Daniel W. McKeel,John C. Morris,John H. Growdon,Bradley T. Hyman +5 more
TL;DR: Stereological principles of neuron counting support the conclusion that a marked decrement of layer II neurons distinguishes even very mild AD from nondemented aging.