J
Joseph M. Mrus
Researcher at Research Triangle Park
Publications - 55
Citations - 2574
Joseph M. Mrus is an academic researcher from Research Triangle Park. The author has contributed to research in topics: Darunavir & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 24, co-authored 55 publications receiving 2294 citations. Previous affiliations of Joseph M. Mrus include GlaxoSmithKline & University of Cincinnati.
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Journal ArticleDOI
Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial
David A. Margolis,Juan González-García,Hans Jürgen Stellbrink,Joseph J. Eron,Yazdan Yazdanpanah,Daniel Podzamczer,Thomas A. Lutz,Jonathan B. Angel,Gary Richmond,Bonaventura Clotet,Félix Gutiérrez,Louis Sloan,Marty St. Clair,Miranda Murray,Susan L. Ford,Joseph M. Mrus,Parul Patel,Herta Crauwels,Sandy Griffith,Kenneth Sutton,David Dorey,Kimberly Y. Smith,Peter Williams,William Spreen +23 more
TL;DR: Both long-acting regimens met primary criteria for comparability in viral suppression relative to the oral comparator group and the primary analysis used a Bayesian approach to evaluate the hypothesis that the proportion with viral suppression for each long- acting regimen is not worse than the oral regimen proportion.
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Spirituality and religion in patients with HIV/AIDS.
Sian Cotton,Christina M. Puchalski,Susan N. Sherman,Joseph M. Mrus,Amy H. Peterman,Judith Feinberg,Kenneth I. Pargament,Amy C. Justice,Anthony C. Leonard,Joel Tsevat +9 more
TL;DR: Most patients with HIV/AIDS belonged to an organized religion and use their religion to cope with their illness, and patients who drink less alcohol tend to be both more spiritual and religious.
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Long-Acting Cabotegravir and Rilpivirine for Maintenance of HIV-1 Suppression
Susan Swindells,Jaime-Federico Andrade-Villanueva,Gary Richmond,Giuliano Rizzardini,Axel Baumgarten,Mar Masiá,Gulam H Latiff,Vadim Pokrovsky,Fritz Bredeek,Graham H R Smith,Pedro Cahn,Yeon Sook Kim,Susan L. Ford,Christine L. Talarico,Parul Patel,Vasiliki Chounta,Herta Crauwels,Wim Louis Julien Parys,Simon Vanveggel,Joseph M. Mrus,Jenny Huang,Conn M. Harrington,Krischan J Hudson,David A. Margolis,Kimberly Y. Smith,Peter Williams,William Spreen +26 more
TL;DR: In this paper, simplified regimens for the treatment of human immunodeficiency virus type 1 (HIV-1) infection may increase patient satisfaction and facilitate adherence, which may improve adherence.
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Gender differences in health-related quality of life in patients with HIV/AIDS
TL;DR: Evaluated gender differences in HRQoL for participants in a large randomized trial comparing antiretroviral regimens found changes in domain scores over time and in response to treatment do not differ significantly by gender, implying that changes indomain scores may be better HRQOL outcomes to compare between HIV-infected men and women in clinical trials than mean domain scores.
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Religion, spirituality, and depressive symptoms in patients with HIV/AIDS
Michael S. Yi,Joseph M. Mrus,Terrance J. Wade,Mona L. Ho,Richard W. Hornung,Sian Cotton,Amy H. Peterman,Christina M. Puchalski,Joel Tsevat +8 more
TL;DR: Poorer health status and perceptions, less social support, and lower spiritual well-being were related to significant depressive symptoms, while personal regligiosity and having a religious affiliation was not associated when controlling for other factors.