J
Josh Neman
Researcher at University of Southern California
Publications - 55
Citations - 1214
Josh Neman is an academic researcher from University of Southern California. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 14, co-authored 44 publications receiving 931 citations. Previous affiliations of Josh Neman include City of Hope National Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Human breast cancer metastases to the brain display GABAergic properties in the neural niche
Josh Neman,John Termini,Sharon Wilczynski,Nagarajan Vaidehi,Cecilia Choy,Claudia M. Kowolik,Hubert Li,Amanda Hambrecht,Eugene Roberts,Rahul Jandial +9 more
TL;DR: The results suggest that breast cancers exhibit neural characteristics when occupying the brain microenvironment and co-opt GABA as an oncometabolite in breast cancer metastases to the brain.
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Regional Delivery of Chimeric Antigen Receptor–Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain
Saul J. Priceman,Dileshni Tilakawardane,Brook Jeang,Brenda Aguilar,John P. Murad,Anthony K. Park,Wen-Chung Chang,Julie R. Ostberg,Josh Neman,Rahul Jandial,Jana Portnow,Stephen J. Forman,Christine E. Brown +12 more
TL;DR: This study shows the importance of CAR design in defining an optimized CAR T cell, and highlights intraventricular delivery of HER2-CAR T cells for treating multifocal brain metastases.
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Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?
Babak Kateb,Katherine Chiu,Keith L. Black,Vicky Yamamoto,Bhavraj Khalsa,Julia Y. Ljubimova,Hui Ding,Rameshwar Patil,Jose Portilla-Arias,Mike Modo,David F. Moore,Keyvan Farahani,Michael S. Okun,Neal Prakash,Josh Neman,Daniel Ahdoot,Warren S. Grundfest,Warren S. Grundfest,Shouleh Nikzad,John D. Heiss +19 more
TL;DR: Advances in nanoplatform, nano-imaging, and nano-drug delivery will drive the future development of nanomedicine, personalized medicine, and targeted therapy and the formation of a science, technology, medicine law-healthcare policy (STML) hub/center could significantly facilitate such advancements and contribute to the translation of nanotechnology across medical disciplines.
Journal ArticleDOI
Altered expression of polycomb group genes in glioblastoma multiforme.
Gang Li,Charles Warden,Zhaoxia Zou,Josh Neman,Joseph S. Krueger,Alisha Jain,Rahul Jandial,Mike Y. Chen +7 more
TL;DR: Aberrant expression of PcG proteins in GBMs may play a role in the development or maintenance of the malignancy.
Journal ArticleDOI
Inhibition of β2-adrenergic receptor reduces triple-negative breast cancer brain metastases: The potential benefit of perioperative β-blockade
Cecilia Choy,John L. Raytis,David D. Smith,Matthew Duenas,Josh Neman,Rahul Jandial,Michael W. Lew +6 more
TL;DR: It is suggested that stress and corresponding β2-activation may promote the establishment of brain metastases of TN breast cancer cells and a benefit to perioperative β-blockade during surgery-induced stress with respect to breast cancer recurrence and metastases.