J
Joshua P. Ramsay
Researcher at Curtin University
Publications - 54
Citations - 1956
Joshua P. Ramsay is an academic researcher from Curtin University. The author has contributed to research in topics: Quorum sensing & Plasmid. The author has an hindex of 18, co-authored 48 publications receiving 1662 citations. Previous affiliations of Joshua P. Ramsay include University of Otago & Murdoch University.
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Journal ArticleDOI
A census of mammalian imprinting
TL;DR: There is a high level of discordance of imprinting status between the mouse and human, even when cases in which the orthologue is absent from one species are excluded, and a high proportion of imprinted genes are noncoding RNAs or genes derived by retrotransposition.
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Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism.
José A. Caparrós-Martín,Ricky R. Lareu,Joshua P. Ramsay,Jörg Peplies,F. Jerry Reen,Henrietta A. Headlam,Natalie C. Ward,Natalie C. Ward,Kevin D. Croft,Philip Newsholme,Jeffery Hughes,Fergal O'Gara +11 more
TL;DR: This study demonstrates that statin therapy drives a profound remodelling of the gut microbiota, hepatic gene deregulation and metabolic alterations in mice through a PXR-dependent mechanism.
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Excision and transfer of the Mesorhizobium loti R7A symbiosis island requires an integrase IntS, a novel recombination directionality factor RdfS, and a putative relaxase RlxS.
TL;DR: It is shown that the ICEMlSymR7AintS gene, which encodes an integrase of the phage P4 family, is required for integration and excision of the island and the presence of a plasmid with cloned island traR traI2 genes resulted in excision in all cells regardless of culture density, indicating that excision may be similarly regulated.
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An updated view of plasmid conjugation and mobilization in Staphylococcus.
Joshua P. Ramsay,Stephen M. Kwong,Riley J. T. Murphy,Karina Yui Eto,Karina J. Price,Quang T. Nguyen,Frances G. O'Brien,Warren B. Grubb,Geoffrey W. Coombs,Neville Firth +9 more
TL;DR: It is suggested that a greater research focus on the molecular biology of conjugation is essential if the accretion and dissemination of antimicrobial-resistance genes in the human and animal pathogen Staphylococcus aureus is to be recognized from increasingly in silico analyses.
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Diverse mobilization strategies facilitate transfer of non-conjugative mobile genetic elements.
Joshua P. Ramsay,Neville Firth +1 more
TL;DR: The findings are summarized, the diverse mobilization strategies employed by mobile genetic elements are reviewed, implications for future gene-transfer research are discussed and more elements may be mobilizable than previously recognized.