J
Juan A. Marchal
Researcher at University of Granada
Publications - 260
Citations - 5723
Juan A. Marchal is an academic researcher from University of Granada. The author has contributed to research in topics: Cancer & Cellular differentiation. The author has an hindex of 36, co-authored 229 publications receiving 4226 citations. Previous affiliations of Juan A. Marchal include University of Jaén & University of Sassari.
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Journal ArticleDOI
Bio-inspired hydrogel composed of hyaluronic acid and alginate as a potential bioink for 3D bioprinting of articular cartilage engineering constructs.
Cristina Antich,Juan de Vicente,Gema Jiménez,Carlos Chocarro,Esmeralda Carrillo,Elvira Montañez,Patricia Gálvez-Martín,Juan A. Marchal +7 more
TL;DR: HA-based bioink was found to improve cell functionality by an increase in the expression of chondrogenic gene markers and specific matrix deposition and, therefore, tissue formation and results indicate that it is a promising bioink candidate for cartilage tissue engineering based in 3D bioprinting.
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Nanomedicine: Application Areas and Development Prospects
Houria Boulaiz,Pablo J. Álvarez,Alberto Ramírez,Juan A. Marchal,Jose Prados,Fernando Rodríguez-Serrano,Macarena Perán,Consolación Melguizo,Antonia Aránega +8 more
TL;DR: In nanomedicine, atoms and molecules are manipulated to produce nanostructures of the same size as biomolecules for interaction with human cells, offering a range of new solutions for diagnoses and “smart” treatments by stimulating the body’s own repair mechanisms.
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Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
Manuel Picon-Ruiz,Manuel Picon-Ruiz,Chendong Pan,Katherine Drews-Elger,Kibeom Jang,Alexandra H. Besser,Dekuang Zhao,Cynthia Morata-Tarifa,Cynthia Morata-Tarifa,Minsoon Kim,Tan A. Ince,Diana J. Azzam,Seth A. Wander,Bin Wang,Burcu Ergonul,Ram H. Datar,Richard J. Cote,Guy A. Howard,Guy A. Howard,Dorraya El-Ashry,Pablo Torné-Poyatos,Juan A. Marchal,Joyce M. Slingerland +22 more
TL;DR: These data support a model in which cancer cell invasion into local fat would establish feed-forward loops to activate Src, maintain proinflammatory cytokine production, and increase tumor-initiating cell abundance and metastatic progression.
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Epigenetic control of retrotransposon expression in human embryonic stem cells.
Angela Macia,Martin Muñoz-Lopez,José Luis Cortés,Robert K. Hastings,Santiago Morell,Gema Lucena-Aguilar,Juan A. Marchal,Richard M. Badge,Jose L. Garcia-Perez +8 more
TL;DR: It is suggested that distinct subsets of active L1/Alu elements are expressed in hESCs and that the degree of somatic mosaicism attributable to L1 insertions during early development may be higher than previously anticipated.
Journal ArticleDOI
Melatonin ameliorates low-grade inflammation and oxidative stress in young Zucker diabetic fatty rats
Ahmad Agil,Russel J. Reiter,Aroa Jiménez-Aranda,Ruth Ibán-Arias,Miguel Navarro-Alarcón,Juan A. Marchal,Abdu Adem,Gumersindo Fernández-Vázquez +7 more
TL;DR: It is demonstrated that oral melatonin administration ameliorates the pro‐inflammatory state and oxidative stress, which underlie the development of insulin resistance and their consequences, metabolic syndrome, diabetes, and cardiovascular disease.