J
Juan Jesus Vicente
Researcher at University of Washington
Publications - 19
Citations - 771
Juan Jesus Vicente is an academic researcher from University of Washington. The author has contributed to research in topics: Microtubule & Dictyostelium discoideum. The author has an hindex of 10, co-authored 18 publications receiving 646 citations. Previous affiliations of Juan Jesus Vicente include University of California, Berkeley & Spanish National Research Council.
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Structural and functional studies of a family of Dictyostelium discoideum developmentally regulated, prestalk genes coding for small proteins
TL;DR: A large family of genes coding for small proteins has been identified in D. discoideum and two groups of very similar genes from this family have been shown to be specifically expressed in prestalk cells during development.
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De novo design of self-assembling helical protein filaments
Hao Shen,Jorge A. Fallas,Eric M. Lynch,William Sheffler,Bradley Parry,N. Jannetty,N. Jannetty,Justin Decarreau,Mike Wagenbach,Juan Jesus Vicente,James K. Chen,James K. Chen,Lai-Sheng Wang,Lai-Sheng Wang,Q. Dowling,Gustav Oberdorfer,Lance Stewart,Linda Wordeman,J. J. De Yoreo,J. J. De Yoreo,Christine Jacobs-Wagner,Christine Jacobs-Wagner,Justin M. Kollman,David Baker +23 more
TL;DR: A general computational approach to designing self-assembling helical filaments from monomeric proteins is described and this approach is used to design proteins that assemble into micrometer-scale filaments with a wide range of geometries in vivo and in vitro.
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Mitosis, microtubule dynamics and the evolution of kinesins
TL;DR: The kinesins involved in each phase of mitosis is reviewed with an emphasis on the stages of mammalian cell division and the role of kines Ins in deep-rooted eukaryotic supergroups.
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Dictyostelium discoideum: a model system for differentiation and patterning.
TL;DR: In Dictyostelium, development begins with the aggregation of free living amoebae, which soon become organized into a relatively simple organism with a few different cell types, and regulates many different signal transduction pathways.
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Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles
TL;DR: A review of microtubule-targeting agents (MTAs) can be found in this paper, where the authors review the mechanism of action of MTAs, the signaling pathways they affect, their impact on cancer and other illnesses, and the promising new therapeutic applications of these classic drugs.