Juan Pellico

TL;DR: In this paper, the authors present a review of the most relevant and up-to-date knowledge available in this field, and support the efficient clinical translation of future nanomedicinal products for in vivo imaging and/or therapy.

TL;DR: This work synthesis and application of a chelator-free 68Ga-iron oxide nanotracer with improved stability, radiolabeling yield and in vivo performance in dual PET/MRI and evaluated these dual targeting nanoparticles in an angiogenesis murine model by PET/MR imaging.

TL;DR: It is shown that genetic and pharmacological interventions affecting oxidative phosphorylation (OXPHOS) modify competition among mtDNA haplotypes during oocyte development and/or at early embryonic stages, and that heteroplasmy behavior can fall on a spectrum from random drift to strong selection, depending on mito-nuclear interactions and metabolic factors.

TL;DR: This review summarises the most relevant examples in the synthesis and biomedical applications of paramagnetic nanoparticles as contrast agents for MRI and multimodal imaging and includes the most recent developments in the field of production of agents with high relaxivities, which are key for effective contrast enhancement.

TL;DR: A review of the reported T1 iron oxide nanoparticles and critically revise their properties, synthetic protocols and application, not only in MRI but also in multimodal imaging to evaluate whether T1Iron oxide nanoparticle can reach Gd/Mn contrast capabilities.