J
Jude Nnaemeka Okoyeh
Researcher at International Centre for Genetic Engineering and Biotechnology
Publications - 6
Citations - 231
Jude Nnaemeka Okoyeh is an academic researcher from International Centre for Genetic Engineering and Biotechnology. The author has contributed to research in topics: Chemistry & Formaldehyde. The author has an hindex of 2, co-authored 2 publications receiving 216 citations.
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Journal ArticleDOI
Plasmodium falciparum Field Isolates Commonly Use Erythrocyte Invasion Pathways That Are Independent of Sialic Acid Residues of Glycophorin A
TL;DR: It may be necessary to target parasite ligands responsible for the alternate invasion pathways in addition to EBA-175 to effectively block erythrocyte invasion by P. falciparum.
Journal ArticleDOI
Hemozoin formation in malaria: a two-step process involving histidine-rich proteins and lipids
Amit V. Pandey,Vinod Babbarwal,Jude Nnaemeka Okoyeh,Ratan Mani Joshi,Sunil K. Puri,Ram Lakhan Singh,Virander S. Chauhan +6 more
TL;DR: It is shown that malarial hemozoin formation is a coordinated two component process involving both lipids and histidine-rich proteins.
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Rhamnetin is a better inhibitor of sars-cov-2 2’-o-methyltransferase than dolutegravir: a computational prediction
Adekunle Babajide Rowaiye,Angus Nnamdi Oli,Olukemi Adejoke Onuh,Nkoli Winifred Emeter,Doofan Bur,Oluwaseun Adeola Obideyi,Oluyomi Cornelius Dayisi,Jude Nnamdi Akpa,Lovelyn Birah,Edward E. Omaka¹,Frances Otibhor Iseghohi¹,Akinbobola Peace Otitoju,Philip F. Uzor,Jude Nnaemeka Okoyeh +13 more
TL;DR: Rhamnetin showed better inhibitory activity at the target’s active site than Dolutegravir at the active site of SARS-CoV-2 2’O-methyltransferase through an in silico approach.
Journal ArticleDOI
Sucrose- and formaldehyde-modified native starches as possible pharmaceutical excipients in tableting
TL;DR: In this paper , the authors used cross-linked maize wheat and rice starches to assess the use of the modified starches as potential excipients [binder] for tableting of paracetamol.
Posted ContentDOI
Virtual Screening of Selected Phytochemicals From Four Antimalarial Plants Predicted Potential Inhibitors of Wild Type and Mutant Forms of Dihydrofolate Reductase-Thymidylate Synthase in Plasmodium sp.
Moses Nkechukwu Ikegbunam,InnocentMary IfedibaluChukwu Ejiofor,Vincent C Duru,Amarachi Akachukwu,Emmanual Oranu,Jude Nnaemeka Okoyeh,Samuel Egieyeh +6 more
TL;DR: This study identifies phytochemicals of Acalypha wilkesiana, Cymbopogon citratus, Azadirachta indica, and Morinda lucida with high binding affinities for the Plasmodium falciparum DHFR-TS and reveals that the receptor-ligand binding of luteolin, the top-ranked, drug like phytochemical, to the quadruple mutant was stable.