Judith Weber

TL;DR: The physical, chemical and biochemical characteristics of the existing photoacoustic contrast agents are critically reviewed, highlighting key applications and present challenges for molecular PAI.

TL;DR: Optoacoustic tomography data acquired with the small-animal OT system were highly repeatable and reproducible across subjects and over time, and longitudinal OT studies may be performed with high confidence when the standard operating procedure is followed.

TL;DR: Thioflavin X, (ThX), a next-generation fluorescent probe which displays superior properties; including a 5-fold increase in brightness and 7-fold increased in binding affinity to amyloidogenic proteins, is designed.

TL;DR: This work describes the design and synthesis of a targeted, activatable probe for photoacoustic imaging, which is responsive to one of the major and abundant reactive oxygen species, hydrogen peroxide (H2O2), and shows promise for the in vivo visualization of hydrogenperoxide.

TL;DR: In this paper, a mathematical model was developed that allows for the calculation of radiation dose rates within small spherical tumors for different distributions of 131I and 125I, and the relationship between tumor size and the therapeutic effects of m -[131I]- and m-[125I]MIBG was studied in vitro using multicellular tumor spheroids of the neuroblastoma cell line SK-N-SH.