Jukka Hytönen

TL;DR: Results suggest that salivary gp340 recognizes different bacterial receptors according to whether gp340 is present in the fluid phase or surface bound, and this phase-associated differential recognition by gp340 of streptococcal species of different levels of virulence and diverse origins may mediate alternative host responses to commensal or pathogenic bacterial phenotypes.

TL;DR: This work identifies strepadhesin, a novel glycoprotein‐binding activity in Streptococcus pyogenes, which is regulated by Mga, a regulator of streptococcal virulence factors, and finds that it is carried by SpeB, strethococcal pyrogenic exotoxin with cysteine protease activity.

TL;DR: CXCL13 outperformed neopterin and appears to be an excellent biomarker in differentiating LNB from viral CNS infections and from other neuroinflammatory conditions.

TL;DR: A national crowdsourcing-based tick collection campaign was organized in 2015 with the objective of producing novel data on tick distribution and tick-borne pathogens in Finland and demonstrates the overwhelming power of citizen science in accomplishing a collection effort that would have been impossible with the scientific community alone.

TL;DR: High strepadhesin activity in an S. pyogenes strain (NZ131rgg) lacking SpeB expression is carried by a surface-bound pullulanase, which combines glycoprotein-binding and carbohydrate-degrading activities in the same molecule.